Wu L Z, Huang Z S, Wu D Z, Chan E
Jpn J Ophthalmol. 1985;29(4):406-11.
The dimensions of the foveal avascular zone (FAZ) were determined on fluorescein angiograms in 45 normal subjects, 25 men and 20 women, by means of a digital image processing system. The shape of the FAZ was usually irregular and showed considerable individual variations. The mean longest diameter was 0.88 +/- 0.16 mm (SD), the horizontal diameter was 0.73 +/- 0.15 mm, vertical diameter was 0.70 +/- 0.17 mm and the area averaged 0.43 +/- 0.16 mm2. The area of the FAZ and the age of the subjects showed a statistically significant positive correlation (r = 0.383, P less than 0.005). The enlargement of the FAZ with advancing age may be related to senescent changes of the retinal capillaries. It was stressed that it is of importance to measure the size of the FAZ by fluorescein angiography before laser photocoagulation is carried out near the macular region.
通过数字图像处理系统，在45名正常受试者（25名男性和20名女性）的荧光血管造影照片上测定了黄斑无血管区（FAZ）的尺寸。FAZ的形状通常不规则，且个体差异较大。平均最长直径为0.88±0.16毫米（标准差），水平直径为0.73±0.15毫米，垂直直径为0.70±0.17毫米，面积平均为0.43±0.16平方毫米。FAZ的面积与受试者年龄呈统计学显著正相关（r = 0.383，P＜0.005）。随着年龄增长FAZ增大可能与视网膜毛细血管的衰老变化有关。强调了在黄斑区附近进行激光光凝治疗前，通过荧光血管造影测量FAZ大小的重要性。
