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感染性骶神经刺激器的治疗:一项范围综述。

Treatment of the infected sacral nerve stimulator: A scoping review.

作者信息

Wynn Jessica, Kelsey Ellen, McLeod Kathryn

机构信息

Department of Urology, University Hospital Geelong, Barwon Health, Geelong, Australia.

Faculty of Health, Deakin University School of Medicine, Geelong, Australia.

出版信息

Neurourol Urodyn. 2024 Mar;43(3):579-594. doi: 10.1002/nau.25411. Epub 2024 Feb 6.

Abstract

BACKGROUND

Sacral nerve stimulators (SNSs) are a widely accepted, efficacious surgical option to treat patients who have failed conservative management for overactive bladder, nonobstructive urinary retention, fecal incontinence, or pelvic pain. As with all implanted devices, there are associated risks for surgical site and implant infections. There are currently no clear published data or guidelines regarding treating such infections.

AIMS

We present a scoping review aiming to examine the existing literature on the treatment approaches of infected SNSs.

METHODS

A scoping review was conducted using Preferred Reporting Items for Systematic Review and Meta-Analysis. The search strategy focused on "sacral modulation," and "infection," and "explantation," and conservative management methods such as "antibiotics." A search was conducted on medical databases, and a grey literature search was performed.

RESULTS

Thirty articles were included for data extraction. Articles were published between 2006 and 2022. Outcomes were reported for 7446 patients. Two hundred and seventy-four infection events were reported, giving an overall 3.7% infection rate. Most infection events were treated with explantation, although there is some discussion on the role of conservative management using oral and intravenous antibiotics in the literature. Articles also discussed considerations for future reimplantation after explantation of SNS.

CONCLUSIONS

There are currently no treatment protocols in the literature to help guide whether a patient is suited to conservative or surgical management. There is future scope for developing treatment algorithms to guide clinicians for optimal treatment of infected sacral neuromodulation devices.

摘要

背景

骶神经刺激器(SNSs)是一种广泛接受且有效的手术选择,用于治疗保守治疗失败的膀胱过度活动症、非梗阻性尿潴留、大便失禁或盆腔疼痛患者。与所有植入设备一样,手术部位和植入物感染存在相关风险。目前尚无关于治疗此类感染的明确公开数据或指南。

目的

我们进行了一项范围综述,旨在研究关于感染SNSs治疗方法的现有文献。

方法

使用系统评价和Meta分析的首选报告项目进行范围综述。搜索策略集中在“骶神经调节”、“感染”、“取出”以及“抗生素”等保守管理方法。在医学数据库中进行搜索,并进行灰色文献搜索。

结果

纳入30篇文章进行数据提取。文章发表于2006年至2022年之间。报告了7446例患者的结果。报告了274例感染事件,总体感染率为3.7%。大多数感染事件采用取出治疗,尽管文献中对使用口服和静脉抗生素进行保守管理的作用有一些讨论。文章还讨论了SNS取出后未来重新植入的注意事项。

结论

目前文献中没有治疗方案来帮助指导患者适合保守治疗还是手术治疗。未来有开发治疗算法的空间,以指导临床医生对感染的骶神经调节设备进行最佳治疗。

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