Zheng Ming-Hui, Liu Wen-Jun, Yang Juan
Division of Cardiovascular First Ward Departments of Internal Medicine, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430077, Hubei Province, China.
Department of Respiratory Medicine, PuRen Hospital Affiliated to Wuhan University of Science and Technology/Respiratory Medicine, Wuhan 430000, Hubei Province, China.
World J Clin Cases. 2024 Feb 6;12(4):729-736. doi: 10.12998/wjcc.v12.i4.729.
Sepsis, as a non-limiting host infection disease, can be accompanied by serious complications such as organ failure, which seriously threatens patient quality of life.
To investigate the effect of early stepwise cardiopulmonary rehabilitation on cardiopulmonary function and quality of life in patients evacuated from mechanical ventilation with sepsis.
A total of 80 patients with sepsis who were hospitalized in our hospital from January 2021 to January 2022 were selected and divided into the observation group ( = 40) and the control group ( = 40) according to the random number table method. The observation group was treated with early stepwise cardiopulmonary rehabilitation, and the control group was treated with a conventional treatment regimen. Cardiac function indexes (central venous pressure, cardiac troponin I, B-type brain natriuretic peptide), lung function indicators (diaphragmatic mobility, changes in central venous oxygen saturation, oxygenation index), and quality of life (Quality of Life Evaluation Scale) were compared between the two groups after treatment.
After treatment, the central venous pressure, diaphragm mobility, central venous oxygen saturation, oxygenation index, and Quality of Life Evaluation Scale scores in the observation group were higher than those in the control group, and the differences were statistically significant ( < 0.05). The observation group was less than that of the control group for other parameters, and the differences were statistically significant ( < 0.05).
Early stepwise cardiopulmonary rehabilitation can effectively enhance cardiac and pulmonary function and improve the quality of life in patients evacuated from mechanical ventilation with sepsis.
脓毒症作为一种无局限的宿主感染性疾病，可伴有器官衰竭等严重并发症，严重威胁患者生活质量。
探讨早期阶段性心肺康复对脓毒症撤机患者心肺功能及生活质量的影响。
选取2021年1月至2022年1月在我院住院的80例脓毒症患者，按随机数字表法分为观察组（n = 40）和对照组（n = 40）。观察组采用早期阶段性心肺康复治疗，对照组采用传统治疗方案。比较两组治疗后心功能指标（中心静脉压、心肌肌钙蛋白I、B型脑钠肽）、肺功能指标（膈肌活动度、中心静脉血氧饱和度变化、氧合指数）及生活质量（生活质量评估量表）。
治疗后，观察组中心静脉压、膈肌活动度、中心静脉血氧饱和度、氧合指数及生活质量评估量表评分均高于对照组，差异有统计学意义（P < 0.05）。观察组其他参数低于对照组，差异有统计学意义（P < 0.05）。
早期阶段性心肺康复可有效增强脓毒症撤机患者的心肺功能，提高其生活质量。
