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抗心磷脂抗体检测以指导Q热治疗

Anticardiolipin Antibody Determination to Guide Q Fever Treatment.

作者信息

Costa Oliveira Diogo, Assis José Guilherme, Linhares Fernanda, Carrola Paulo

机构信息

Intensive Care Unit, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, PRT.

Internal Medicine, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, PRT.

出版信息

Cureus. 2024 Jan 8;16(1):e51840. doi: 10.7759/cureus.51840. eCollection 2024 Jan.

Abstract

Query (Q) fever is a worldwide infectious disease with acute and chronic manifestations caused by . The clinical manifestations are so variable that the disease is often only diagnosed if systematically considered as a differential diagnosis. Here, we present a case of a 39-year-old man who lived in a countryside house, with cattle and sheep in his field, with acute Q fever hepatitis with the typical granulomatous arrangement in the liver biopsy. The diagnosis was confirmed by (PCR) assay in a serum sample and the presence of phase II antibodies. Anticardiolipin antibody (aCL) determination at diagnosis of acute Q fever and during follow-up was made to persecute early identification and to guide the treatment and prophylaxis of possible complications, such as endocarditis.

摘要

疑问热(Q热)是一种由……引起的、具有急性和慢性表现的全球性传染病。其临床表现变化多样,以至于常常只有在将其作为鉴别诊断进行系统考虑时才能确诊。在此,我们报告一例39岁男性病例,该男子居住在乡下的一所房子里,其田地里饲养着牛羊,患有急性Q热肝炎,肝活检显示典型的肉芽肿排列。血清样本的……(聚合酶链反应)检测以及II期抗体的存在证实了诊断。在急性Q热诊断时及随访期间进行抗心磷脂抗体(aCL)检测,以追踪早期识别情况,并指导对可能并发症(如心内膜炎)的治疗和预防。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa80/10847898/09d62b7f65af/cureus-0016-00000051840-i01.jpg

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