Wechsler J, Clerici T, Capron F, Ghozali F, Martin N, André P, Touraine R, Pinaudeau Y
Ann Pathol. 1985;5(4-5):271-8.
5 cases of angiolymphoid hyperplasia with eosinophilia of the skin are reported. This rare condition was initially described in 1969 by Wells and Whimster. The microscopical pattern is characterised by an atypical vascular proliferation associated with an eosinophilic and lymphoplasmocytic granuloma. In our series, immunohistological study demonstrated the polyclonality of the plasmacytoid component. Electron microscopy performed in one case shows endothelial features even in cells forming clusters without well-defined lumen. These results support the endothelial origin of angiolymphoid hyperplasia with eosinophilia.
报告了5例皮肤嗜酸性粒细胞增多性血管淋巴样增生症。这种罕见病症最初由威尔斯和惠姆斯特于1969年描述。显微镜下表现为非典型血管增生，并伴有嗜酸性粒细胞和淋巴浆细胞性肉芽肿。在我们的病例系列中，免疫组织学研究证实了浆细胞样成分的多克隆性。对1例患者进行的电子显微镜检查显示，即使在形成无明确管腔的细胞团簇的细胞中也具有内皮细胞特征。这些结果支持嗜酸性粒细胞增多性血管淋巴样增生症的内皮起源。
