Alagha Abdullah M, Bahlas Sami M, Alariefy Abdulaziz A, Alqarni Saher F, Almahyawi Faisal A, Alariefy Saleh A
Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.
Rheumatology Division, Internal Medicine, King Abdulaziz University, Jeddah, SAU.
Cureus. 2024 Jan 9;16(1):e51929. doi: 10.7759/cureus.51929. eCollection 2024 Jan.
Background The immune system, composed of various molecules and cells, protects humans from cancer and pathogens. A breach of tolerance, known as autoimmune disease (AD), is the root of these diseases. Systemic lupus erythematosus (SLE) is an autoimmune condition characterized by chronic inflammation, causing tissue damage in various organ systems. The disease is influenced by hormonal, environmental, and genetic factors. The pathophysiology is unclear, and 20% to 30% of patients have a persistent illness. SLE affects young females more than males, and treatments focus on organ manifestations. Despite advancements and better diagnoses, SLE continues to contribute significantly to morbidity and early mortality. Objective This study aims to assess knowledge of SLE among the general population of Jeddah, Saudi Arabia. Methodology An online cross-sectional survey using Google Forms was conducted for Jeddah residents aged 18 and above. The survey was open for responses from August 2023 to October 2023. Results The study included 479 participants, with 19 (25%) males and 57 (75%) females diagnosed with SLE. The majority of these individuals were housewives and unemployed. The majority were married (46, 60.5%), with only 25 (32.9%) being single. Among healthy participants, there were 173 (42.9%) males and 230 (57.1%) females, with a majority being housewives and government employees (95, 23.6%). Singles accounted for 124 (30.8%), while married individuals constituted 253 (62.8%). Among the healthy population respondents, 254 (63%) lacked knowledge about SLE treatment, while 40 (52.6%) SLE patients believed that a combination of chemotherapy, malaria medication, and steroids was the best treatment. The study found that 393 (82%) of the sample had heard about SLE, and 250 (52%) believed it was not a contagious disease. More than 30 were unaware of SLE. The majority of the respondents felt they needed more awareness and health promotion about SLE, with 410 (85.77%) stating they needed more promotion. The majority of the people believed SLE was dangerous to some extent. Conclusions This study revealed the need and necessity of awareness of SLE among the general community of Jeddah. We advocate undertaking disease awareness programs and activities to increase general community knowledge and awareness of SLE in the city of Jeddah.
背景 免疫系统由各种分子和细胞组成，保护人类免受癌症和病原体侵害。耐受性的破坏，即自身免疫性疾病（AD），是这些疾病的根源。系统性红斑狼疮（SLE）是一种自身免疫性疾病，其特征为慢性炎症，会导致各个器官系统的组织损伤。该疾病受激素、环境和遗传因素影响。其病理生理学尚不清楚，20%至30%的患者病情持续。SLE对年轻女性的影响大于男性，治疗重点在于器官表现。尽管取得了进展且诊断有所改善，但SLE仍然是发病率和早期死亡率的重要原因。
目的 本研究旨在评估沙特阿拉伯吉达普通人群对SLE的了解情况。
方法 对吉达18岁及以上居民进行了一项使用谷歌表单的在线横断面调查。该调查于2023年8月至2023年10月开放接受回复。
结果 该研究纳入了479名参与者，其中19名（25%）男性和57名（75%）女性被诊断为SLE。这些个体中的大多数是家庭主妇和失业者。大多数人已婚（46人，60.5%），只有25人（32.9%）单身。在健康参与者中，有173名（42.9%）男性和230名（57.1%）女性，大多数是家庭主妇和政府雇员（95人，23.6%）。单身者占124人（30.8%），已婚者占253人（62.8%）。在健康人群受访者中，254人（63%）对SLE治疗缺乏了解，而40名（52.6%）SLE患者认为化疗、抗疟疾药物和类固醇联合使用是最佳治疗方法。该研究发现，样本中有393人（82%）听说过SLE，250人（52%）认为它不是传染病。超过30人不知道SLE。大多数受访者认为他们需要更多关于SLE的认识和健康宣传，410人（85.77%）表示他们需要更多宣传。大多数人认为SLE在某种程度上是危险的。
结论 本研究揭示了吉达普通社区对SLE认识的必要性。我们主张开展疾病宣传项目和活动，以增加吉达市普通社区对SLE的知识和认识。
