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Vedolizumab Does Not Affect Antibody Secreting Cell Recruitment to the Lactating Mammary Gland of Mothers With Inflammatory Bowel Disease.

作者信息

Urrete Josef, Mitra Taniya, Boland Brigid S, Bertrand Kerri, Chambers Christina, Rivera-Nieves Jesús

机构信息

Division of Gastroenterology, University of California San Diego, La Jolla, CA, USA.

GI Section, San Diego VA Medical Center (SDVAMC), San Diego, CA, USA.

出版信息

Inflamm Bowel Dis. 2025 Jan 6;31(1):290-293. doi: 10.1093/ibd/izae023.

DOI:10.1093/ibd/izae023
PMID:38334263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11700889/
Abstract
摘要

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Association of Vedolizumab Level, Anti-Drug Antibodies, and α4β7 Occupancy With Response in Patients With Inflammatory Bowel Diseases. vedolizumab 水平、抗药物抗体和 α4β7 占有率与炎症性肠病患者反应的相关性。
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本文引用的文献

1
Stability and heterogeneity in the antimicrobiota reactivity of human milk-derived immunoglobulin A.人乳来源免疫球蛋白 A 对微生物反应的稳定性和异质性。
J Exp Med. 2023 Aug 7;220(8). doi: 10.1084/jem.20220839. Epub 2023 Jul 18.
2
Safety of Ustekinumab and Vedolizumab During Pregnancy-Pregnancy, Neonatal, and Infant Outcome: A Prospective Multicentre Study.优特克单抗和维得利珠单抗在妊娠期的安全性-妊娠、新生儿和婴儿结局：一项前瞻性多中心研究。
J Crohns Colitis. 2022 Dec 5;16(12):1808-1815. doi: 10.1093/ecco-jcc/jjac086.
3
The multifaceted roles of breast milk antibodies.母乳抗体的多效性作用。
Cell. 2021 Mar 18;184(6):1486-1499. doi: 10.1016/j.cell.2021.02.031.
4
The Design and Mechanics of an Accessible Human Milk Research Biorepository.易于使用的人乳研究生物库的设计与力学。
Breastfeed Med. 2020 Mar;15(3):155-162. doi: 10.1089/bfm.2019.0277. Epub 2020 Jan 27.
5
Pregnancy outcomes in inflammatory bowel disease patients treated with vedolizumab, anti-TNF or conventional therapy: results of the European CONCEIVE study.接受维得利珠单抗、抗 TNF 或常规治疗的炎症性肠病患者的妊娠结局：欧洲 CONCEIVE 研究结果。
Aliment Pharmacol Ther. 2020 Jan;51(1):129-138. doi: 10.1111/apt.15539. Epub 2019 Nov 6.
6
The Profile of Human Milk Metabolome, Cytokines, and Antibodies in Inflammatory Bowel Diseases Versus Healthy Mothers, and Potential Impact on the Newborn.人乳代谢组、细胞因子和抗体在炎症性肠病与健康母亲中的特征，及其对新生儿的潜在影响。
J Crohns Colitis. 2019 Mar 30;13(4):431-441. doi: 10.1093/ecco-jcc/jjy186.
7
Outcome of Pregnancies in Female Patients With Inflammatory Bowel Diseases Treated With Vedolizumab.接受维得利珠单抗治疗的炎症性肠病女性患者的妊娠结局。
J Crohns Colitis. 2019 Jan 1;13(1):12-18. doi: 10.1093/ecco-jcc/jjy142.
8
An increase in milk IgA correlates with both pIgR expression and IgA plasma cell accumulation in the lactating mammary gland of PRM/Alf mice.在 PRM/Alf 小鼠的哺乳期乳腺中，牛奶 IgA 的增加与 pIgR 表达和 IgA 浆细胞的积累都相关。
J Reprod Immunol. 2012 Dec;96(1-2):25-33. doi: 10.1016/j.jri.2012.08.001. Epub 2012 Sep 25.
9
Breastfeeding and the risk for diarrhea morbidity and mortality.母乳喂养与腹泻发病率和死亡率的关系。
BMC Public Health. 2011 Apr 13;11 Suppl 3(Suppl 3):S15. doi: 10.1186/1471-2458-11-S3-S15.
10
IgA ASC accumulation to the lactating mammary gland is dependent on VCAM-1 and alpha4 integrins.IgA ASC 在哺乳期乳腺中的积累依赖于 VCAM-1 和 alpha4 整合素。
Mol Immunol. 2010 Apr;47(7-8):1608-12. doi: 10.1016/j.molimm.2010.01.015. Epub 2010 Feb 19.