Administrative Office, Yuebei People's Hospital, Medical College, Shantou University, Shaoguan, Guangdong, China.
Quality Management Department, Yuebei People's Hospital, Medical College, Shantou University, Shaoguan, Guangdong, China.
Front Public Health. 2024 Jun 27;12:1399192. doi: 10.3389/fpubh.2024.1399192. eCollection 2024.
Providing the human papillomavirus (HPV) vaccine is effective to eliminate the disparity in HPV-related cancers. It is unknown regarding inequality in the distribution of HPV vaccination in China since the vaccine was licensed and approved for use in 2016. This study aimed to examine socioeconomic inequalities in HPV-related knowledge and vaccination and identified factors associated with such inequalities.
Self-administered questionnaires measuring HPV-related knowledge and vaccine uptake were completed by 1,306 women through online survey platform. HPV knowledge was assessed using a 12-item question stem that covered the hazards of HPV infection, HPV vaccine dosage, benefits, and protection. Cluster analysis by combining monthly household income, educational level, and employment status was used to identify socioeconomic status (SES) class. The concentration index (CI) was employed as a measure of socioeconomic inequalities in HPV-related knowledge and vaccination. Linear regression and logistic regression were established to decompose the contributions of associated factors to the observed inequalities.
The CI for HPV-related knowledge and vaccine uptake was 0.0442 and 0.1485, respectively, indicating the higher knowledge and vaccination rate were concentrated in groups with high SES. Education and household income made the largest contribution to these inequalities. Age, residency and cervical cancer screening were also important contributors of observed inequalities.
Socioeconomic inequalities in HPV-related knowledge and vaccination uptake are evident in China. Interventions to diffuse HPV-related information for disadvantaged groups are helpful to reduce these inequalities. Providing low or no-cost HPV vaccination and ensuring accessibility of vaccines in rural areas are also considered to be beneficial.
提供人乳头瘤病毒（HPV）疫苗可有效消除 HPV 相关癌症方面的差异。自 2016 年该疫苗获得许可和批准使用以来，中国尚不清楚 HPV 疫苗接种分布方面的不平等现象。本研究旨在探讨 HPV 相关知识和疫苗接种方面的社会经济不平等现象，并确定与这些不平等现象相关的因素。
通过在线调查平台，1306 名女性完成了自我管理问卷，以测量 HPV 相关知识和疫苗接种情况。HPV 知识通过涵盖 HPV 感染危害、HPV 疫苗剂量、益处和保护的 12 项问题来评估。采用结合月家庭收入、教育水平和就业状况的聚类分析来确定社会经济地位（SES）类别。集中指数（CI）用于衡量 HPV 相关知识和疫苗接种方面的社会经济不平等。线性回归和逻辑回归用于分解相关因素对观察到的不平等现象的贡献。
HPV 相关知识和疫苗接种的 CI 分别为 0.0442 和 0.1485，表明较高的知识和接种率集中在 SES 较高的群体中。教育和家庭收入对这些不平等现象的贡献最大。年龄、居住地和宫颈癌筛查也是观察到的不平等现象的重要贡献因素。
中国 HPV 相关知识和疫苗接种方面存在社会经济不平等现象。为弱势群体传播 HPV 相关信息的干预措施有助于减少这些不平等现象。提供低成本或免费的 HPV 疫苗接种，并确保在农村地区获得疫苗，也被认为是有益的。
