Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi Kamimachi, Itabashi-ku, Tokyo, 173-8610, Japan.
Department of Digestive Surgery, Nihon University School of Medicine, Tokyo, Japan.
J Med Ultrason (2001). 2024 Apr;51(2):301-309. doi: 10.1007/s10396-024-01408-0. Epub 2024 Feb 9.
No studies of the relationship between grayscale sonographic findings and pancreatic fat content have been reported to date. This study aimed to investigate the correlation between echogenicity and fat content of resected specimens using quantitative analysis.
Forty-two consecutive patients who underwent pancreatoduodenectomy or distal pancreatectomy for pancreatic tumors were enrolled in this study. Ultrasonographic images were compared with quantitative pathological analysis. Subjective evaluation of echogenicity was classified as hypoechoic, isoechoic, hyperechoic, and super hyperechoic. The total and intralobular fat areas were measured.
The mean, median, modal, minimum, and maximum ultrasound gray values correlated with the proportion of total fat area (r = 0.349; 0.357, 0.486, 0.466, and 0.347; p = 0.024, 0.020, 0.014, 0.019, and 0.089, respectively), but did not correlate with the proportion of intralobular fat area. Subjective classification was correlated with median gray value (p < 0.001), intralobular fat area (p = 0.118), and total fat area (p = 0.011). Cases were classified as hypoechoic (n = 3), isoechoic (n = 7), hyperechoic (n = 30), and super hyperechoic (n = 2). The subjective classification was correlated with the median gray value (p < 0.001) and total fat area (p = 0.005), and not correlated with the intralobular fat area (p = 0.118). Hyperechoic or super hyperechoic pancreatic parenchyma contains over 19.7% fat. Computed tomography values correlated with the proportion of intralobular fat area (r = - 0.479, p = 0.004) and total fat area (r = - 0.541, p < 0.001).
Echogenicity classified based on subjective evaluation and image analysis were correlated with the proportion of fat in the pancreas.
目前尚无研究报道灰阶超声表现与胰腺脂肪含量之间的关系。本研究旨在通过定量分析探讨回声与切除标本脂肪含量之间的相关性。
本研究纳入了 42 例因胰腺肿瘤而行胰十二指肠切除术或胰体尾切除术的连续患者。将超声图像与定量病理分析进行比较。回声强度的主观评估分为低回声、等回声、高回声和超高回声。测量总的和小叶内的脂肪面积。
平均、中位数、众数、最小和最大超声灰度值与总脂肪面积比例相关（r=0.349；0.357、0.486、0.466、0.347；p=0.024、0.020、0.014、0.019 和 0.089），但与小叶内脂肪面积比例无关。主观分类与中位数灰度值（p<0.001）、小叶内脂肪面积（p=0.118）和总脂肪面积（p=0.011）相关。病例分为低回声（n=3）、等回声（n=7）、高回声（n=30）和超高回声（n=2）。主观分类与中位数灰度值（p<0.001）和总脂肪面积（p=0.005）相关，与小叶内脂肪面积无关（p=0.118）。高回声或超高回声胰腺实质含有超过 19.7%的脂肪。CT 值与小叶内脂肪面积比例（r=-0.479，p=0.004）和总脂肪面积比例（r=-0.541，p<0.001）相关。
基于主观评估和图像分析的回声强度分类与胰腺脂肪含量比例相关。
