Li Shilin, Su Liyang, Lv Guorong, Zhao Weihong, Chen Jianhui
Department of Ultrasonography, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Medicine (Baltimore). 2017 Sep;96(37):e8060. doi: 10.1097/MD.0000000000008060.
The aim of our study was to investigate the rate of nonalcoholic fatty pancreas disease (NAFPD) in the south China province of Fujian and its relationship to nonalcoholic fatty liver disease (NAFLD) and metabolic parameters.NAFPD is frequently identified on transabdominal ultrasound examination. The incidence of NAFPD varies from 16% to 69.7% depending on the country.A total of 256 subjects were recruited. Each was assessed by abdominal sonography to diagnose NAFLD and NAFPD. The ages, sexes, heights, weights, blood pressure, and detection of peripheral blood biochemical indices (cholesterol, triglycerides, high-density lipoprotein cholesterol [HDL], low-density lipoprotein cholesterol [LDL], and glucose) were recorded. The relationships among metabolic parameters and NAFPD or NAFLD were evaluated, and the positive rates of NAFLD and NAFPD in the general population were compared.The age, systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI), cholesterol, triglycerides, HDL, LDL, and glucose were significantly associated with NAFPD and NAFLD but the positive rate of NAFPD was significantly higher than that of NAFLD. The BMI, age, and NAFLD were the independent risk factors of NAFPD. The sex distribution, weight, SBP, DBP, BMI, LDL, HDL, triglycerides, glucose, cholesterol, NAFPD, and NAFLD were different significantly between metabolic syndrome and normal subjects.NAFPD and NAFLD can reflect the body metabolism, but NAFPD has a higher detection rate.
我们研究的目的是调查中国南方福建省非酒精性脂肪性胰腺疾病(NAFPD)的发生率及其与非酒精性脂肪性肝病(NAFLD)和代谢参数的关系。NAFPD常在经腹超声检查中被发现。NAFPD的发病率因国家而异,在16%至69.7%之间。共招募了256名受试者。通过腹部超声检查对每个人进行评估,以诊断NAFLD和NAFPD。记录年龄、性别、身高、体重、血压以及外周血生化指标(胆固醇、甘油三酯、高密度脂蛋白胆固醇[HDL]、低密度脂蛋白胆固醇[LDL]和血糖)的检测结果。评估代谢参数与NAFPD或NAFLD之间的关系,并比较普通人群中NAFLD和NAFPD的阳性率。年龄、收缩压(SBP)、舒张压(DBP)、体重指数(BMI)、胆固醇、甘油三酯、HDL、LDL和血糖与NAFPD和NAFLD显著相关,但NAFPD的阳性率显著高于NAFLD。BMI、年龄和NAFLD是NAFPD的独立危险因素。代谢综合征患者与正常受试者在性别分布、体重、SBP、DBP、BMI、LDL、HDL、甘油三酯、血糖、胆固醇、NAFPD和NAFLD方面存在显著差异。NAFPD和NAFLD都能反映身体代谢情况,但NAFPD的检出率更高。