Liu Lingling, Fisher Kaleb D, Bussey William D
Department of Agricultural and Biosystems Engineering, Iowa State University, Ames, IA 50010, USA.
Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50010, USA.
Polymers (Basel). 2024 Feb 1;16(3):415. doi: 10.3390/polym16030415.
Recent focus on cellulose nanomaterials, particularly biodegradable and biocompatible cellulose nanocrystals (CNCs), has prompted their use as emulsion stabilizers. CNCs, when combined with salt, demonstrate enhanced emulsion stabilization. This study explored three emulsion stabilizers: Tween 80, soybean CNCs with salt (salted CNCs), and a combination of salted CNCs with Tween 80. Soybean CNCs, derived from soybean stover, were characterized by Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). Antifungal testing against revealed increased bioactivity in all lemongrass essential oil (EO)-loaded emulsions compared to pure essential oil. In addition, all three emulsions exhibited a slight reduction in antifungal activity after 30 days of room temperature storage. The release experiment revealed that the EO-loaded nanoemulsion exhibited a slow-release profile. The nanoemulsion stabilized by salted CNCs and Tween 80 exhibited significantly lower release rates when compared to the nanoemulsion stabilized solely by Tween 80, attributed to the gel network formed by salted CNCs. The findings of this study highlight the efficacy of cellulose nanocrystals procured from soybean byproducts in conjunction with synthetic surfactants to create nanoencapsulated essential oils, resulting in improved antimicrobial efficacy and the achievement of sustained release properties.
最近对纤维素纳米材料的关注，特别是可生物降解和生物相容的纤维素纳米晶体（CNCs），促使它们被用作乳液稳定剂。当CNCs与盐结合时，表现出增强的乳液稳定性。本研究探索了三种乳液稳定剂：吐温80、加盐的大豆CNCs（盐化CNCs）以及盐化CNCs与吐温80的组合。从大豆秸秆中提取的大豆CNCs通过傅里叶变换红外光谱（FTIR）、X射线衍射（XRD）、差示扫描量热法（DSC）和热重分析（TGA）进行了表征。针对[未提及具体测试对象]的抗真菌测试表明，与纯香茅精油相比，所有负载香茅精油（EO）的乳液的生物活性均有所提高。此外，在室温储存30天后，所有三种乳液的抗真菌活性均略有降低。释放实验表明，负载EO的纳米乳液呈现出缓释曲线。与仅由吐温80稳定的纳米乳液相比，由盐化CNCs和吐温80稳定的纳米乳液的释放速率显著更低，这归因于盐化CNCs形成的凝胶网络。本研究结果突出了从大豆副产品中获得的纤维素纳米晶体与合成表面活性剂结合用于制备纳米包封精油的功效，从而提高了抗菌效果并实现了缓释性能。
