Zheng Lixiang, Shi Lidan, Wu Xiangzhe, Hu Panyang, Zhang Ben, Han Xuelei, Wang Kejun, Li Xiuling, Yang Feng, Wang Yining, Li Xinjian, Qiao Ruimin
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Animals (Basel). 2024 Jan 24;14(3):374. doi: 10.3390/ani14030374.
Saliva is an important exocrine fluid that is easy to collect and is a complex mixture of proteins and other molecules from multiple sources from which considerable biological information can be mined. Pig saliva, as an easily available biological liquid rich in bioactive ingredients, is rich in nucleic acid analytes, such as eggs, enzymes, amino acids, sugars, etc. The expression levels of these components in different diseases have received extensive attention, and the analysis of specific proteins, metabolites, and biological compositions in pig saliva has become a new direction for disease diagnosis and treatment. The study of the changes in analytes in pig saliva can provide a new strategy for early diagnosis, prognosis assessment, and treatment of diseases. In this paper, the detection methods and research progress of porcine salivary analytes are reviewed, the application and research progress of porcine salivary analytes in diseases are discussed, and the future application prospect is presented.
唾液是一种重要的外分泌液，易于采集，是来自多种来源的蛋白质和其他分子的复杂混合物，从中可以挖掘出大量生物信息。猪唾液作为一种易于获取且富含生物活性成分的生物液体，富含核酸分析物，如蛋类、酶、氨基酸、糖类等。这些成分在不同疾病中的表达水平受到广泛关注，对猪唾液中特定蛋白质、代谢物和生物成分的分析已成为疾病诊断和治疗的新方向。研究猪唾液中分析物的变化可为疾病的早期诊断、预后评估和治疗提供新策略。本文综述了猪唾液分析物的检测方法及研究进展，讨论了猪唾液分析物在疾病中的应用及研究进展，并展望了其未来应用前景。
