• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

小麦转录共抑制子 TaTPR1 抑制易感性基因并增强对 的穿透后抗性。

Wheat Transcriptional Corepressor TaTPR1 Suppresses Susceptibility Genes and Potentiates Post-Penetration Resistance against .

机构信息

College of Life Sciences, Qingdao University, Qingdao 266071, China.

出版信息

Int J Mol Sci. 2024 Jan 30;25(3):1695. doi: 10.3390/ijms25031695.

DOI:10.3390/ijms25031695
PMID:38338970
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10855895/
Abstract

The obligate biotrophic fungal pathogen () is the causal agent of wheat powdery mildew disease. The TOPLESS-related 1 (TPR1) corepressor regulates plant immunity, but its role in regulating wheat resistance against powdery mildew remains to be disclosed. Herein, TaTPR1 was identified as a positive regulator of wheat post-penetration resistance against powdery mildew disease. The transient overexpression of or confers wheat post-penetration resistance powdery mildew, while the silencing of and results in an enhanced wheat susceptibility to Furthermore, () and () were identified as wheat susceptibility () genes facilitating a infection. The overexpression of and leads to an enhanced wheat susceptibility to , while the silencing of wheat and leads to a compromised susceptibility to powdery mildew. In addition, we demonstrated that the expression of and is negatively regulated by the wheat transcriptional corepressor TaTPR1. Collectively, these results implicate that TaTPR1 positively regulates wheat post-penetration resistance against powdery mildew probably via suppressing the genes and .

摘要

专性生物营养型真菌病原体 () 是小麦白粉病的致病因子。TOPLESS 相关 1 (TPR1) 核心抑制子调节植物免疫，但它在调节小麦对白粉病的抗性方面的作用仍有待揭示。在此，我们鉴定出 TaTPR1 是小麦抗白粉病后侵染的正调控因子。过表达 或 赋予小麦对白粉病的后侵染抗性，而沉默 和 则导致小麦对 的易感性增强。此外， 和 被鉴定为促进 感染的小麦感病 () 基因。 和 的过表达导致小麦对 的易感性增强，而小麦 和 的沉默则导致对白粉病的易感性降低。此外，我们证明了 的表达受小麦转录核心抑制子 TaTPR1 的负调控。总之，这些结果表明 TaTPR1 通过抑制小麦 基因 和 来正向调控小麦对白粉病的后侵染抗性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/21a5df2e1a5d/ijms-25-01695-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/0bd81f6b20c2/ijms-25-01695-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/ed3c4a8a77ad/ijms-25-01695-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/873dd2c17ebb/ijms-25-01695-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/c69a2bdda12c/ijms-25-01695-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/66bbfb6fac02/ijms-25-01695-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/21a5df2e1a5d/ijms-25-01695-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/0bd81f6b20c2/ijms-25-01695-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/ed3c4a8a77ad/ijms-25-01695-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/873dd2c17ebb/ijms-25-01695-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/c69a2bdda12c/ijms-25-01695-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/66bbfb6fac02/ijms-25-01695-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a1b/10855895/21a5df2e1a5d/ijms-25-01695-g006.jpg

相似文献

1
Wheat Transcriptional Corepressor TaTPR1 Suppresses Susceptibility Genes and Potentiates Post-Penetration Resistance against .小麦转录共抑制子 TaTPR1 抑制易感性基因并增强对 的穿透后抗性。
Int J Mol Sci. 2024 Jan 30;25(3):1695. doi: 10.3390/ijms25031695.
2
Wheat Genes and Negatively Regulate Post-Penetration Resistance against .小麦基因负调控对 的穿透后抗性。
Int J Mol Sci. 2023 Jun 16;24(12):10224. doi: 10.3390/ijms241210224.
3
The Wheat Mediator Subunit TaMED25 Interacts with the Transcription Factor TaEIL1 to Negatively Regulate Disease Resistance against Powdery Mildew.小麦中介亚基TaMED25与转录因子TaEIL1相互作用，负向调控对白粉病的抗病性。
Plant Physiol. 2016 Mar;170(3):1799-816. doi: 10.1104/pp.15.01784. Epub 2016 Jan 26.
4
Histone Deacetylase TaHDT701 Functions in TaHDA6-TaHOS15 Complex to Regulate Wheat Defense Responses to f.sp. .组蛋白去乙酰化酶 TaHDT701 在 TaHDA6-TaHOS15 复合物中发挥功能，以调节小麦对 f.sp.. 的防御反应。
Int J Mol Sci. 2020 Apr 10;21(7):2640. doi: 10.3390/ijms21072640.
5
TaCRT3 Is a Positive Regulator of Resistance to f. sp. in Wheat.TaCRT3是小麦对叶锈菌抗性的正向调控因子。
Phytopathology. 2024 Mar;114(3):641-652. doi: 10.1094/PHYTO-08-23-0276-R. Epub 2024 Mar 18.
6
Evidence for Allele-Specific Levels of Enhanced Susceptibility of Wheat Mutants to the Hemibiotrophic Fungal Pathogen pv. .小麦突变体对半活体营养型真菌病原菌 pv. 的等位基因特异性增强易感性的证据。
Genes (Basel). 2020 May 7;11(5):517. doi: 10.3390/genes11050517.
7
Simultaneous modification of three homoeologs of TaEDR1 by genome editing enhances powdery mildew resistance in wheat.通过基因组编辑同时修饰三个 TaEDR1 同系物可增强小麦对白粉病的抗性。
Plant J. 2017 Aug;91(4):714-724. doi: 10.1111/tpj.13599. Epub 2017 Jun 13.
8
Virulence of Egyptian Blumeria graminis f. sp. tritici Population and Response of Egyptian Wheat Cultivars.埃及小麦叶锈菌群体的毒性及埃及小麦品种的反应。
Plant Dis. 2018 Feb;102(2):391-397. doi: 10.1094/PDIS-07-17-0975-RE. Epub 2017 Nov 21.
9
The NB-LRR gene Pm60 confers powdery mildew resistance in wheat.基因 Pm60 赋予小麦对白粉病的抗性。
New Phytol. 2018 Apr;218(1):298-309. doi: 10.1111/nph.14964. Epub 2017 Dec 27.
10
TaEDS1 genes positively regulate resistance to powdery mildew in wheat.TaEDS1 基因正向调控小麦对白粉病的抗性。
Plant Mol Biol. 2018 Apr;96(6):607-625. doi: 10.1007/s11103-018-0718-9. Epub 2018 Mar 26.

引用本文的文献

1
Wheat Chromatin Remodeling Protein TaSWP73 Contributes to Compatible Wheat-Powdery Mildew Interaction.小麦染色质重塑蛋白TaSWP73有助于小麦与白粉菌的亲和互作。
Int J Mol Sci. 2025 Mar 13;26(6):2590. doi: 10.3390/ijms26062590.
2
Wheat MIXTA-like Transcriptional Activators Positively Regulate Cuticular Wax Accumulation.小麦类 MIXTA 转录激活因子正向调控角质层蜡质的积累。
Int J Mol Sci. 2024 Jun 14;25(12):6557. doi: 10.3390/ijms25126557.

本文引用的文献

1
Transcription Factor TaMYB30 Activates Wheat Wax Biosynthesis.转录因子 TaMYB30 激活小麦蜡的生物合成。
Int J Mol Sci. 2023 Jun 16;24(12):10235. doi: 10.3390/ijms241210235.
2
Wheat Genes and Negatively Regulate Post-Penetration Resistance against .小麦基因负调控对 的穿透后抗性。
Int J Mol Sci. 2023 Jun 16;24(12):10224. doi: 10.3390/ijms241210224.
3
Arabidopsis Topless-related 1 mitigates physiological damage and growth penalties of induced immunity.拟南芥 Topless 相关蛋白 1 减轻诱导免疫的生理损伤和生长缺陷。
New Phytol. 2023 Aug;239(4):1404-1419. doi: 10.1111/nph.19054. Epub 2023 Jun 12.
4
Long-term and rapid evolution in powdery mildew fungi.白粉菌真菌的长期和快速进化。
Mol Ecol. 2024 May;33(10):e16909. doi: 10.1111/mec.16909. Epub 2023 Mar 20.
5
Wheat Class III Peroxidase TaPOD70 Is a Potential Susceptibility Factor Negatively Regulating Wheat Resistance to f. sp. .小麦类 III 过氧化物酶 TaPOD70 是一个潜在的易感性因子，负调控小麦对条锈菌的抗性。
Phytopathology. 2023 May;113(5):873-883. doi: 10.1094/PHYTO-01-23-0001-FI. Epub 2023 Jun 21.
6
Combating powdery mildew: Advances in molecular interactions between f. sp. and wheat.防治白粉病：小麦白粉菌与小麦之间分子相互作用的研究进展
Front Plant Sci. 2022 Dec 16;13:1102908. doi: 10.3389/fpls.2022.1102908. eCollection 2022.
7
Priming seeds for the future: Plant immune memory and application in crop protection.为未来播种：植物免疫记忆及其在作物保护中的应用。
Front Plant Sci. 2022 Jul 29;13:961840. doi: 10.3389/fpls.2022.961840. eCollection 2022.
8
Evolution and origin of bread wheat.小麦的进化和起源。
Plant Cell. 2022 Jul 4;34(7):2549-2567. doi: 10.1093/plcell/koac130.
9
TOPLESS in the regulation of plant immunity.植物免疫调控中的全裸蛋白
Plant Mol Biol. 2022 May;109(1-2):1-12. doi: 10.1007/s11103-022-01258-9. Epub 2022 Mar 28.
10
Genome-edited powdery mildew resistance in wheat without growth penalties.编辑基因组提高小麦对白粉病的抗性而不影响生长。
Nature. 2022 Feb;602(7897):455-460. doi: 10.1038/s41586-022-04395-9. Epub 2022 Feb 9.