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摩洛哥初级保健机构使用者中慢性阻塞性肺疾病的患病率及危险因素。

Prevalence and Risk Factors of Chronic Obstructive Pulmonary Disease Among Users of Primary Health Care Facilities in Morocco.

机构信息

Hassan First University of Settat, Higher Institute of Health Sciences, Laboratory of Sciences and Health Technologies, Settat, 26000, Morocco.

Laboratory of Microbial Biotechnology & Bioactive Molecules, Faculty of Science and Technology, University Sidi Mohammed Ben Abdellah Fez, Fez, BP 2202, Morocco.

出版信息

Int J Chron Obstruct Pulmon Dis. 2024 Feb 5;19:375-387. doi: 10.2147/COPD.S443081. eCollection 2024.

Abstract

BACKGROUND

Chronic obstructive pulmonary disease (COPD) is a major public health problem. In Morocco, few studies have focused on COPD in primary health care facilities, whose main mission is prevention. The aim of our work is thus to assess the prevalence of COPD and to study the factors associated with this silent disease among users of health care facilities in Morocco.

METHODS

This is a cross-sectional observational study of participants aged 40 and over. Data were collected by questionnaire. Pulmonary function testing was conducted using a spirometer before and after administration of a bronchodilator. COPD was defined as fixed ratio of the post-bronchodilator forced expiratory volume in 1 second / forced vital capacity less than 0.7. Logistic regression models were applied to define factors associated with COPD.

RESULTS

From 550 participants aged 40 and over, we selected only 477 patients with exploitable spirometry results for inclusion in the final analysis. The mean age of participants was 54.91±11.92 years, and the female/male ratio was 1.59. The prevalence of COPD was 6.7% (95% CI; 4.6 to 9.3%), and was higher in men than in women (11.4% vs 3.8%, p=0.002). The prevalence of COPD increased significantly with age, from 3.3% in those aged 40 to 49 to 16.9% in those aged 70 and over (p=0.001). Current smokers had a higher prevalence of COPD than former and never smokers. Age, smoking, asthma diagnosis and childhood hospitalization for lung disease were risk factors associated with the development of COPD. Only 6.25% of participants identified as having COPD had previously been diagnosed with COPD.

CONCLUSION

COPD remains largely under-diagnosed among primary care consultants in Morocco. Efforts for early detection and promotion of prevention of the main risk factors need to be intensified in order to reduce the burden of this silent pathology on a national scale.

摘要

背景

慢性阻塞性肺疾病(COPD)是一个主要的公共卫生问题。在摩洛哥,很少有研究关注初级保健设施中的 COPD,而初级保健设施的主要任务是预防。因此,我们的工作目的是评估 COPD 的患病率,并研究摩洛哥医疗保健设施使用者中与这种沉默疾病相关的因素。

方法

这是一项横断面观察性研究,参与者年龄在 40 岁及以上。数据通过问卷收集。在使用支气管扩张剂后进行肺活量测定,使用肺活量计进行肺功能测试。COPD 的定义为支气管扩张剂后 1 秒用力呼气量/用力肺活量的固定比值小于 0.7。应用逻辑回归模型来确定与 COPD 相关的因素。

结果

在 550 名年龄在 40 岁及以上的参与者中,我们仅选择了 477 名可进行可利用的肺活量测定结果的患者纳入最终分析。参与者的平均年龄为 54.91±11.92 岁,男女比例为 1.59。COPD 的患病率为 6.7%(95%置信区间:4.6%至 9.3%),男性高于女性(11.4%比 3.8%,p=0.002)。COPD 的患病率随年龄显著增加,从 40 至 49 岁人群的 3.3%增加到 70 岁及以上人群的 16.9%(p=0.001)。当前吸烟者比既往吸烟者和从不吸烟者更易患 COPD。年龄、吸烟、哮喘诊断和儿童因肺部疾病住院是与 COPD 发展相关的危险因素。仅有 6.25%的被识别为患有 COPD 的参与者之前曾被诊断患有 COPD。

结论

在摩洛哥,初级保健顾问对 COPD 的诊断仍然严重不足。需要加强早期发现和促进预防主要危险因素的努力,以减轻这种沉默病理学在全国范围内的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a59/10854398/7fca6ba3c116/COPD-19-375-g0001.jpg

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