Benslimane Abdelilah, Garcia-Larsen Vanessa, El Kinany Khaoula, Alaoui Chrifi Amina, Hatime Zineb, Benjelloun Mohamed Chakib, El Biaze Mohammed, Nejjari Chakib, El Rhazi Karima
Department of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Fez, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
SAGE Open Med. 2021 Jul 17;9:20503121211031428. doi: 10.1177/20503121211031428. eCollection 2021.
The Moroccan cross-sectional study aimed to investigate obesity in association to chronic obstructive pulmonary disease in Fez city.
A cross-sectional survey was carried out in Moroccan adults. Anthropometric and spirometry measurements were performed using standardized guidelines.
Among the 744 participants, 53.9% of were women, with a mean age of 55.27 years (SD = 10.29). Nearly all women declared themselves to be never smokers, while 21% of men were current smokers. Overall, chronic obstructive pulmonary disease prevalence decreased with body mass index ( = 0.01) and waist circumference ( < 0.001). The same trends were also observed in women. The adjusted regression analysis showed a significant independent association between chronic obstructive pulmonary disease and decreasing overweight (OR: 0.66; CI (0.40-0.98)), obesity (OR: 0.66 CI: (0.36-0.89)), and a decreasing waist circumference-abdominal obesity (OR: 0.58 CI: (0.34-0.99)) in the whole population. The same association remains significant in women for overweight (OR: 0.18 CI: (0.06-0.54)) and for waist circumference-abdominal obesity (OR: 0.40 CI: (0.19-0.85)). All these associations disappeared for men.
Chronic obstructive pulmonary disease decreases with the increase in body mass index and waist circumference. The effect of waist circumference on the chronic obstructive pulmonary disease was greater among women, regardless of the tobacco factor. A multicenter study would help to confirm the accuracy of these findings in a larger sample of the Moroccan population. Developed lifestyle programs in patients with chronic obstructive pulmonary disease should be considered.
摩洛哥的这项横断面研究旨在调查非斯市肥胖与慢性阻塞性肺疾病之间的关联。
对摩洛哥成年人进行了一项横断面调查。使用标准化指南进行人体测量和肺功能测定。
在744名参与者中，53.9%为女性，平均年龄为55.27岁（标准差 = 10.29）。几乎所有女性称自己从不吸烟，而21%的男性为当前吸烟者。总体而言，慢性阻塞性肺疾病患病率随体重指数降低（P = 0.01）和腰围减小（P < 0.001）而下降。在女性中也观察到了相同趋势。校正回归分析显示，在整个人口中，慢性阻塞性肺疾病与超重减轻（比值比：0.66；可信区间（0.40 - 0.98））、肥胖减轻（比值比：0.66，可信区间：（0.36 - 0.89））以及腰围 - 腹部肥胖减轻（比值比：0.58，可信区间：（0.34 - 0.99））之间存在显著的独立关联。在女性中，超重（比值比：0.18，可信区间：（0.06 - 0.54））和腰围 - 腹部肥胖（比值比：0.40，可信区间：（0.19 - 0.85））的相同关联仍然显著。在男性中，所有这些关联均消失。
慢性阻塞性肺疾病随体重指数和腰围增加而降低。无论烟草因素如何，腰围对慢性阻塞性肺疾病的影响在女性中更大。多中心研究将有助于在更大的摩洛哥人群样本中证实这些发现的准确性。应考虑为慢性阻塞性肺疾病患者制定生活方式项目。
