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评估 COPD 评估测试(CAT)在筛查慢性阻塞性肺疾病中的有效性。

Evaluating the Effectiveness of the COPD Assessment Test (CAT) in Screening for Chronic Obstructive Pulmonary Disease.

机构信息

Hassan First University of Settat, Higher Institute of Health Sciences, Laboratory of Sciences and Health Technologies, Settat, 26000, Morocco.

Higher Institute of Nursing Professions and Health Techniques (ISPITS), Casablanca, Morocco.

出版信息

Int J Chron Obstruct Pulmon Dis. 2024 Jul 11;19:1623-1633. doi: 10.2147/COPD.S460649. eCollection 2024.

DOI:10.2147/COPD.S460649
PMID:39011121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11249108/
Abstract

BACKGROUND

Chronic obstructive pulmonary disease (COPD) is a major public health problem that remains largely under-diagnosed, mainly due to the under-use of spirometry to establish the diagnosis. The aim of this study is to evaluate the effectiveness of the Moroccan Arabic dialect version of the COPD Assessment Test (CAT) in screening for COPD.

METHODS

This was a cross-sectional study carried out in primary care facilities in Morocco, involving participants aged 40 and over. The performance of CAT in detecting cases of COPD was measured with reference to the results of spirometry, considered to be the gold Standard.

RESULTS

A total of 477 participants were included in the study. The prevalence of COPD was 6.7%. Internal consistency of the Moroccan Arabic dialect version of the CAT was high, with a Cronbach's alpha of 0.89. The total score of the CAT and of each item was significantly higher in subjects with COPD than in those without (P=0.000). Significantly negative correlations were found between CAT total score and FEV1 (r = -0.33, p=0.000), CAT and FVC (r = -0.22, p=0.000), CAT and FEV1/FVC ratio (r = -0.22, p=0.000). The receiver operating characteristic curve showed an area under the curve of 0.93. A CAT score of 10 was the optimal cut-off value for COPD screening, with a sensitivity, specificity, positive predictive value, and negative predictive value of 78.1%, 93.9%, 48.1% and 98.4%, respectively.

CONCLUSION

The results of the present study showed that the CAT could be used as a screening tool for COPD. The use of this tool by healthcare professionals in primary care settings will improve and promote early diagnosis of this chronic disease.

摘要

背景

慢性阻塞性肺疾病(COPD)是一个主要的公共卫生问题,主要由于肺量计诊断的使用率低,导致大部分 COPD 患者未能得到确诊。本研究旨在评估摩洛哥阿拉伯语版 COPD 评估测试(CAT)在 COPD 筛查中的有效性。

方法

这是一项在摩洛哥基层医疗机构进行的横断面研究,纳入了 40 岁及以上的参与者。通过与被认为是金标准的肺量计结果进行比较,评估 CAT 在检测 COPD 病例中的表现。

结果

共有 477 名参与者纳入研究。COPD 的患病率为 6.7%。CAT 的摩洛哥阿拉伯语版内部一致性较高,Cronbach's alpha 为 0.89。CAT 总分和每个项目的得分在 COPD 患者中明显高于非 COPD 患者(P=0.000)。CAT 总分与 FEV1(r = -0.33,p=0.000)、CAT 与 FVC(r = -0.22,p=0.000)、CAT 与 FEV1/FVC 比值(r = -0.22,p=0.000)之间存在显著负相关。受试者工作特征曲线下面积为 0.93。CAT 评分 10 分是 COPD 筛查的最佳截断值,其敏感度、特异度、阳性预测值和阴性预测值分别为 78.1%、93.9%、48.1%和 98.4%。

结论

本研究结果表明,CAT 可作为 COPD 的筛查工具。在基层医疗机构中,医疗保健专业人员使用该工具将有助于改善和促进对这种慢性疾病的早期诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a54/11249108/1cb1c6e6b5d5/COPD-19-1623-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a54/11249108/185b661c6779/COPD-19-1623-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a54/11249108/1cb1c6e6b5d5/COPD-19-1623-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a54/11249108/185b661c6779/COPD-19-1623-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a54/11249108/1cb1c6e6b5d5/COPD-19-1623-g0002.jpg

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