Primary Care Research Unit of Salamanca (APISAL), Salamanca Primary Care Management, Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
Intensive Care Unit, Salamanca University Hospital, Salamanca, Spain.
Front Public Health. 2024 Jan 26;12:1322437. doi: 10.3389/fpubh.2024.1322437. eCollection 2024.
Behavioral and substance addictions are prevalent health problems that, alongside obesity, are linked to reduced physical activity and increased sedentary time. Similarly, arterial stiffness and vascular aging are processes that begin gradually at an early age and are closely associated with morbidity and mortality from cardiovascular diseases. The main objective of this study is to analyze how addictions are related to obesity and body fat distribution, physical activity, sedentary time, arterial stiffness and vascular aging, as well as sleep quality, cognitive function and gender differences in young adults aged between 18 and 34 years.
This cross-sectional descriptive observational study will analyze data from 500 subjects (250 men and 250 women) aged 18-34 without cardiovascular disease, selected by simple random sampling with replacement from the urban population of the city center of Salamanca (34,044 people aged 18-34, with 18,450 women and 15,594 men). Behavioral and substance addictions, as well as sleep quality and cognitive impairment will be assessed using questionnaires. The Pittisburg Sleep Quality Index (PSQI) will be used to measure sleep quality and the Ford questionnaire will be used to measure insomnia in response to stress. For obesity, weight, height, waist and hip circumference, body composition will be measured with the impedance meter. For physical activity and sedentary time, we will use the accelerometer alongside the international physical activity questionnaire (IPAQ) and the Marshall questionnaire. The will be used for pulse wave analysis and carotid-femoral pulse wave velocity (cfPWV), while the will measure cardio ankle vascular index (CAVI) and brachial-ankle pulse wave velocity (baPWV). Vascular aging will be calculated with the 10th and 90th percentiles of cfPWV or baPWV. Demographic, analytical variables will be collected, as will data to assess vascular, cardiac, renal, and brain injury.
Addictions are on the rise in today's society, affecting the mental health and well-being of those who suffer from them, generating important social problems such as job loss, family dysfunction, debt and social isolation. Together with obesity, they are prevalent health problems in young adults and are associated with lower physical activity and higher sedentary time. Meanwhile, arterial stiffness and vascular aging are processes that begin gradually at an early age and determine morbidity and mortality caused by cardiovascular diseases. The results of this project will allow us to understand the situation regarding behavioral and substance addictions in young adults. Better understanding of these addictions will in turn facilitate the development of more effective prevention strategies and intervention programs, which can then reduce the negative impact at both the individual and societal levels.
[ClinicalTrials.gov], identifier [NCT05819840].
行为和物质成瘾是普遍存在的健康问题，与肥胖一起，与体力活动减少和久坐时间增加有关。同样，动脉僵硬和血管老化是一个从早期开始逐渐发生的过程，与心血管疾病的发病率和死亡率密切相关。本研究的主要目的是分析成瘾与肥胖和体脂分布、体力活动、久坐时间、动脉僵硬和血管老化以及年轻人的睡眠质量、认知功能和性别差异之间的关系，年龄在 18 至 34 岁之间。
这是一项横断面描述性观察研究，将分析 500 名（250 名男性和 250 名女性）年龄在 18-34 岁、无心血管疾病的受试者的数据，这些受试者通过市中心城市人口的简单随机抽样（34044 名年龄在 18-34 岁的人，其中 18450 名女性和 15594 名男性）进行替换。使用问卷评估行为和物质成瘾以及睡眠质量和认知障碍。匹兹堡睡眠质量指数（PSQI）将用于衡量睡眠质量，而福特问卷将用于衡量压力下的失眠。肥胖、体重、身高、腰围和臀围、身体成分将使用阻抗计进行测量。对于体力活动和久坐时间，我们将使用加速度计以及国际体力活动问卷（IPAQ）和马歇尔问卷。脉搏波分析和颈股脉搏波速度（cfPWV）将使用脉搏波分析仪进行测量，而心血管脚踝血管指数（CAVI）和肱踝脉搏波速度（baPWV）将使用动脉硬化检测仪进行测量。血管老化将通过 cfPWV 或 baPWV 的第 10 和第 90 百分位进行计算。将收集人口统计学、分析变量以及评估血管、心脏、肾脏和大脑损伤的数据。
在当今社会，成瘾现象日益增多，影响着那些受其影响的人的心理健康和幸福感，产生了失业、家庭功能障碍、债务和社会孤立等重要的社会问题。肥胖症一起，它们是年轻人中普遍存在的健康问题，与较低的体力活动和较高的久坐时间有关。与此同时，动脉僵硬和血管老化是一个从早期开始逐渐发生的过程，决定了心血管疾病的发病率和死亡率。该项目的结果将使我们能够了解年轻人中行为和物质成瘾的情况。更好地了解这些成瘾将有助于制定更有效的预防策略和干预计划，从而减少个人和社会层面的负面影响。
[ClinicalTrials.gov]，标识符 [NCT05819840]。
