全球儿童和青少年 1990 年至 2019 年所有病因特异性伤害负担:一项前瞻性队列研究。

Global burden of all cause-specific injuries among children and adolescents from 1990 to 2019: a prospective cohort study.

机构信息

Department of ophthalmology, Guangdong Eye Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University.

School of Medicine South China University of Technology.

出版信息

Int J Surg. 2024 Apr 1;110(4):2092-2103. doi: 10.1097/JS9.0000000000001131.

Abstract

BACKGROUND

To assess the burden and change in incidence, death, and disability-adjusted life years (DALYs) for all-cause-specific injuries among children and adolescents in 204 countries and territories between 1990 and 2019.

MATERIALS AND METHODS

Data were extracted from the Global Burden of Disease, Injury, and Risk Factor Study 2019 (GBD 2019). Global, regional, and country-level age-standardized rate (per 100 000) of incidence (ASRI), mortality (ASRM), and DALYs (ASRD) with 95% uncertainty interval (95% UI) of injuries were estimated by age, sex, socio-demographic index (SDI), and all-cause-specific injuries from 1990 to 2019.

RESULTS

Overall, the ASRI, ASRM, and ASRD of injury were 9006.18 (95% UI: 7459.74-10 918.04), 23.04 (20.00-26.50), and 2020.19 (1759.47-2318.64) among children and adolescents worldwide in 2019, respectively. All the above indicators showed a downward trend from 1990 to 2019. In level 2 cause of injury, both the global transport injury and unintentional injury declined during the study years, while self-harm and interpersonal violence-related injury showed an increasing trend. High SDI regions had higher ASRI of injuries, but low SDI regions had higher ASRM and ASRD of injuries globally in 2019. Males had a higher burden of injuries than those in females. The ASRI of injuries is higher in adolescents aged 15-19 years, whereas the mortality and DALYs rate are higher among children under 5 years old. Moreover, adolescents aged 15-19 years and individuals living in Central Asia, Middle East, and Africa had higher ASRI, ASRM, and ASRD of injuries owing to self-harm and interpersonal violence. Generally, falls and road traffic injuries are the leading cause of injury among the population aged 0-19 years worldwide, but self-harm, interpersonal violence, and conflict and terrorism are also leading types of injuries in some regions, particularly in Low-Income Countries and Middle-Income Countries.

CONCLUSIONS

Injury remains a major global public health problem among children and adolescents, although its burden at the worldwide level showed a decreasing trend from 1990 to 2019. Of concern, the burden of injuries caused by transport injuries, and unintentional injuries has shown a downward trend in most countries, while the burden caused by self-harm and interpersonal violence has shown an upward trend in most countries. These findings suggest that more targeted and specific strategies to prevent the burden of injuries should be reoriented, and our study provides important findings for decision-makers and healthcare providers to reduce injury burden among children and adolescents.

摘要

背景

评估全球 204 个国家和地区 1990 年至 2019 年期间所有病因特异性伤害的负担和发生率、死亡率以及伤残调整生命年(DALY)的变化。

材料和方法

数据来自全球疾病、伤害和危险因素研究 2019 年(GBD 2019)。通过年龄、性别、社会人口指数(SDI)和 1990 年至 2019 年所有病因特异性伤害,估计全球、区域和国家层面每 100000 人的年龄标准化发生率(ASRI)、死亡率(ASRM)和伤残调整生命年(ASRD),置信区间为 95%(95%UI)。

结果

2019 年,全球儿童和青少年的伤害 ASRI、ASRM 和 ASRD 分别为 9006.18(95%UI:7459.74-10918.04)、23.04(20.00-26.50)和 2020.19(1759.47-2318.64)。所有这些指标都呈下降趋势。在伤害的 2 级病因中,全球交通伤害和非故意伤害都在研究期间下降,而自我伤害和人际暴力相关伤害呈上升趋势。高 SDI 地区的伤害 ASRI 更高,但全球高 SDI 地区的伤害 ASRM 和 ASRD 更高。男性的伤害负担高于女性。15-19 岁青少年的伤害 ASRI 更高,而 5 岁以下儿童的死亡率和 DALY 率更高。此外,由于自我伤害和人际暴力,15-19 岁青少年和中亚、中东和非洲地区的个人的伤害 ASRI、ASRM 和 ASRD 更高。一般来说,全球 0-19 岁人群中伤害的主要原因是跌倒和道路交通伤害,但在一些地区,自我伤害、人际暴力和冲突与恐怖主义也是主要伤害类型,特别是在低收入国家和中等收入国家。

结论

尽管全球范围内,1990 年至 2019 年伤害负担呈下降趋势,但伤害仍然是儿童和青少年的一个主要全球公共卫生问题。令人担忧的是,大多数国家的交通伤害和非故意伤害导致的伤害负担呈下降趋势,而大多数国家的自我伤害和人际暴力导致的伤害负担呈上升趋势。这些发现表明,应重新调整针对伤害负担的更有针对性和具体的策略,我们的研究为决策者和医疗保健提供者提供了重要的发现,以减轻儿童和青少年的伤害负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/866b/11020088/60e795f8737d/js9-110-2092-g001.jpg

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