Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing 400030, People's Republic of China.
Department of Ultrasound, University-Town Hospital of Chongqing Medical University, Chongqing 400042, People's Republic of China.
Biofabrication. 2024 Feb 22;16(2). doi: 10.1088/1758-5090/ad28f0.
This study endeavors to investigate the progression, research focal points, and budding trends in the realm of skin bioprinting over the past decade from a structural and temporal dynamics standpoint. Scholarly articles on skin bioprinting were obtained from WoSCC. A series of bibliometric tools comprising R software, CiteSpace, HistCite, and an alluvial generator were employed to discern historical characteristics, evolution of active topics, and upcoming tendencies in the area of skin bioprinting. Over the past decade, there has been a consistent rise in research interest in skin bioprinting, accompanied by an extensive array of meaningful scientific collaborations. Concurrently, diverse dynamic topics have emerged during various periods, as substantiated by an aggregate of 22 disciplines, 74 keywords, and 187 references demonstrating citation bursts. Four burgeoning research subfields were discerned through keyword clustering-namely, #3 'bioprinting', #6 'vascular', #7 'xanthan gum', and #8 'collagen hydrogels'. The keyword alluvial map reveals that Module 1, including 'transplantation' etc, has primarily dominated the research module over the previous decade, maintaining enduring relevance despite annual shifts in keyword focus. Additionally, we mapped out the top six key modules from 2023 being 'silk fibroin nanofiber', 'system', 'ionic liquid', 'mechanism', and 'foot ulcer'. Three recent research subdivisions were identified via timeline visualization of references, particularly Clusters #0 'wound healing', #4 'situ mineralization', and #5 '3D bioprinter'. Insights derived from bibliometric analyses illustrate present conditions and trends in skin bioprinting research, potentially aiding researchers in pinpointing central themes and pioneering novel investigative approaches in this field.
本研究旨在从结构和时间动态的角度,调查过去十年中皮肤生物打印领域的进展、研究重点和新兴趋势。从 WoSCC 获取了有关皮肤生物打印的学术文章。使用一系列计量学工具,包括 R 软件、CiteSpace、HistCite 和冲积生成器,以辨别皮肤生物打印领域的历史特征、活跃主题的演变和未来趋势。在过去的十年中,人们对皮肤生物打印的研究兴趣持续增加,同时也进行了广泛的有意义的科学合作。同时,在不同时期出现了不同的动态主题,这一点得到了 22 个学科、74 个关键词和 187 个参考文献的综合证明,这些参考文献显示出引文爆发。通过关键词聚类,发现了四个新兴的研究子领域,分别是#3“生物打印”、#6“血管”、#7“黄原胶”和#8“胶原蛋白水凝胶”。关键词冲积图显示,模块 1 包括“移植”等,在过去十年中主要主导着研究模块,尽管每年的关键词重点都在变化,但仍然具有持久的相关性。此外,我们还绘制了 2023 年排名前六的关键模块,分别是“丝素纳米纤维”、“系统”、“离子液体”、“机制”和“足部溃疡”。通过参考文献的时间线可视化,发现了三个新的研究细分领域,特别是聚类#0“伤口愈合”、#4“原位矿化”和#5“3D 生物打印机”。从文献计量分析中获得的见解说明了皮肤生物打印研究的现状和趋势,这可能有助于研究人员确定该领域的核心主题,并开创新的研究方法。