Sitamahalakshmi Koppu, Krishna Bingi Sai, Krishna Kumar Govardhani, Bhuvanesh Yanamala, Keerthi Sai Surapaneni, Parkavi Subramanyam
Department of Periodontology & Implantology, Kamineni Institute of Dental Sciences, Narketpally, Nalgonda, India.
Department of Conservative Dentistry & Endodontics Kamineni Institute of Dental Sciences, Narketpally, Nalgonda, India.
Bioinformation. 2024 Jan 31;20(1):85-90. doi: 10.6026/973206300200085. eCollection 2024.
The risk of further periodontal breakdown increases with a deep intrabony defect. Non-surgical periodontal therapy could pose a challenge and surgical intervention is mainly required to manage the defect. Autologous platelet concentrates such as Injectable platelet rich fibrin (i-PRF) and concentrated growth factor (CGF) may improve surgical outcome due to its enrichment with growth factors. Total of 04 patients involved in this study. After conventional flap debridement of intrabony defects, CGF is placed in 2 patients and the other 2 patients received i-PRF in their respective intrabony defects. Volumetric analysis was done pre-operative and 6 months post operatively in both the groups. Bone volume is significantly increased in both CGF and i-PRF group but higher in CGF group when compared to i-PRF group has high regenerative and reconstructive growth factors which helps aids in early and high bone fill when compared to i-PRF.
骨内深袋会增加牙周进一步破坏的风险。非手术牙周治疗可能具有挑战性，主要需要手术干预来处理该缺损。自体血小板浓缩物，如可注射富血小板纤维蛋白（i-PRF）和浓缩生长因子（CGF），因其富含生长因子，可能会改善手术效果。本研究共纳入4例患者。在对骨内缺损进行常规翻瓣清创后，2例患者植入CGF，另外2例患者在各自的骨内缺损处接受i-PRF治疗。两组均在术前和术后6个月进行体积分析。CGF组和i-PRF组的骨体积均显著增加，但与i-PRF组相比，CGF组更高，CGF组具有较高的再生和重建生长因子，与i-PRF相比，有助于早期大量骨填充。
