舌下静脉曲张与高血压的关系：系统评价和荟萃分析。

Relationship between sublingual varices and hypertension: a systematic review and meta-analysis.

机构信息

Department of Oral and Maxillofacial Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

BMC Oral Health. 2024 Feb 15;24(1):240. doi: 10.1186/s12903-024-03982-8.

DOI:10.1186/s12903-024-03982-8

PMID:38360643

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10868067/

Abstract

BACKGROUND

Previous research has investigated the connection between sublingual varices (SV) and cardiovascular disease, aging, and smoking. However, it is still unclear whether arterial hypertension affects the presence of SV. This meta-analysis aimed to investigate the relationship between hypertension and the presence of SV.

METHODS

The literature search was performed using PubMed, Web of Science, Scopus, Google Scholar, and Embase for cross-sectional studies until July 2023. PRISMA guidelines were used for article selection. A meta-analysis using standardized mean differences by a random effects model was conducted to pool studies.

RESULTS

A total of 568 articles were retrieved, of which twelve were included in the meta-analysis. Cumulatively, 2543 samples in the case group (1185 with hypertension) and 3897 samples (821 with hypertension) were studied in the control group. Using the random effects model, the pooled odds ratio (OR) revealed a significant association between hypertension and sublingual varices (OR = 2.66; 95% CI: 1.69-4.18).

CONCLUSION

The meta-analysis showed a significant and positive association between sublingual varices and hypertension. SV's presence could be used by dentists as a non-invasive indicator of hypertension screening.

摘要

背景

先前的研究已经探讨了舌下静脉曲张 (SV) 与心血管疾病、衰老和吸烟之间的联系。然而，动脉高血压是否会影响 SV 的存在仍不清楚。本荟萃分析旨在研究高血压与 SV 存在之间的关系。

方法

使用 PubMed、Web of Science、Scopus、Google Scholar 和 Embase 进行文献检索，截至 2023 年 7 月，检索了横断面研究。使用 PRISMA 指南进行文章选择。使用随机效应模型的标准化均数差值进行荟萃分析以汇总研究结果。

结果

共检索到 568 篇文章，其中 12 篇被纳入荟萃分析。累积研究中，病例组（1185 例高血压）共有 2543 个样本，对照组（821 例高血压）共有 3897 个样本。使用随机效应模型，荟萃分析得出的合并比值比 (OR) 表明，高血压与舌下静脉曲张之间存在显著关联（OR=2.66；95%CI：1.69-4.18）。