糖尿病患者红细胞山梨醇脱氢酶活性水平降低。
Reduced levels of erythrocyte sorbitol dehydrogenase activity in human diabetics.
作者信息
Barretto O C, Ursich M, Nonoyama K
出版信息
Braz J Med Biol Res. 1985;18(4):477-9.
Erythrocyte sorbitol dehydrogenase activity was significantly lower for 34 diabetic patients (mean +/- SD: 0.219 +/- 0.085 U min-1 g Hb-1) than for 27 normal blood donors (0.34 +/- 0.094 U min-1 g Hb-1). This finding agrees with the previous report of low sorbitol dehydrogenase activity in the lens of diabetic patients but contrasts with the data of Crabbe and collaborators (M.J.C. Crabbe, A.B. Halder, C.O. Peckar and H. Cheng, Lancet, 2: 1268-1270, 1980) who found a large variation in the levels of the diabetic population and which was not significantly different from the normal control.
34名糖尿病患者的红细胞山梨醇脱氢酶活性（均值±标准差：0.219±0.085 U min-1 g Hb-1）显著低于27名正常献血者（0.34±0.094 U min-1 g Hb-1）。这一发现与之前关于糖尿病患者晶状体中山梨醇脱氢酶活性较低的报道一致，但与Crabbe及其合作者的数据（M.J.C. Crabbe、A.B. Halder、C.O. Peckar和H. Cheng，《柳叶刀》，2：1268 - 1270，1980）形成对比，他们发现糖尿病患者群体的水平存在很大差异，且与正常对照组无显著差异。
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