Guangzhou Huashang Vocational College, Guangzhou, 510000, China.
Guangdong Agriculture Industry Business Polytechnic, Guangzhou, 510000, China.
Anal Sci. 2024 Apr;40(4):581-597. doi: 10.1007/s44211-024-00515-9. Epub 2024 Feb 17.
The domains of cancer therapy, disease prevention, and health care greatly benefit from the use of herbal medicine. Herbal medicine has become the mainstay of developing characteristic agriculture in the planting area increasing year by year. One of the most significant factors in affecting the quality of herbal medicines is the pesticide residue problem caused by pesticide abuse during the cultivation of herbal medicines. It is urgent to solve the problem of detecting pesticide residues in herbal medicines efficiently and rapidly. In this review, we provide a comprehensive description of the various methods used for pesticide residue testing, including optical detection, the enzyme inhibition rate method, molecular detection methods, enzyme immunoassays, lateral immunochromatographic, nanoparticle-based detection methods, colorimetric immunosensor, chemiluminescence immunosensor, smartphone-based immunosensor, etc. On this basis, we systematically analyze the mechanisms and some of the findings of the above detection strategies and discuss the challenges and prospects associated with the development of pesticide residue detection tools.
癌症治疗、疾病预防和医疗保健领域极大地受益于草药的使用。草药已成为种植面积逐年增加的特色农业发展的支柱。影响草药质量的最重要因素之一是在草药种植过程中滥用农药导致的农药残留问题。迫切需要有效地、快速地解决草药中农药残留的检测问题。在这篇综述中，我们全面描述了用于农药残留检测的各种方法，包括光学检测、酶抑制率法、分子检测方法、酶免疫测定、侧向免疫层析、基于纳米颗粒的检测方法、比色免疫传感器、化学发光免疫传感器、基于智能手机的免疫传感器等。在此基础上，我们系统地分析了上述检测策略的机制和部分研究结果，并讨论了开发农药残留检测工具所面临的挑战和前景。
