HRB Clinical Research Facility, Mercy University Hospital, University College Cork, Cork City, T12 WE28, Ireland.
Department of Emergency Medicine and Emergency Care Research Core, Washington University in St. Louis School of Medicine, St. Louis, MO 63110-1010, USA.
Age Ageing. 2024 Feb 1;53(2). doi: 10.1093/ageing/afae013.
Frailty is associated with adverse outcomes among patients attending emergency departments (EDs). While multiple frailty screens are available, little is known about which variables are important to incorporate and how best to facilitate accurate, yet prompt ED screening. To understand the core requirements of frailty screening in ED, we conducted an international, modified, electronic two-round Delphi consensus study.
A two-round electronic Delphi involving 37 participants from 10 countries was undertaken. Statements were generated from a prior systematic review examining frailty screening instruments in ED (logistic, psychometric and clinimetric properties). Reflexive thematic analysis generated a list of 56 statements for Round 1 (August-September 2021). Four main themes identified were: (i) principles of frailty screening, (ii) practicalities and logistics, (iii) frailty domains and (iv) frailty risk factors.
In Round 1, 13/56 statements (23%) were accepted. Following feedback, 22 new statements were created and 35 were re-circulated in Round 2 (October 2021). Of these, 19 (54%) were finally accepted. It was agreed that ideal frailty screens should be short (<5 min), multidimensional and well-calibrated across the spectrum of frailty, reflecting baseline status 2-4 weeks before presentation. Screening should ideally be routine, prompt (<4 h after arrival) and completed at first contact in ED. Functional ability, mobility, cognition, medication use and social factors were identified as the most important variables to include.
Although a clear consensus was reached on important requirements of frailty screening in ED, and variables to include in an ideal screen, more research is required to operationalise screening in clinical practice.
虚弱与急诊科(ED)就诊患者的不良结局相关。虽然有多种虚弱筛查工具,但对于哪些变量对于纳入以及如何最好地促进准确、快速的 ED 筛查至关重要,人们知之甚少。为了了解 ED 中虚弱筛查的核心要求,我们进行了一项国际性的、经过改良的、两轮电子 Delphi 共识研究。
我们开展了一项两轮电子 Delphi 研究,参与者来自 10 个国家的 37 名人员。研究从先前的系统综述中获取了关于 ED 中虚弱筛查工具(逻辑、心理测量和临床测量特性)的语句。反思性主题分析生成了第一轮(2021 年 8 月至 9 月)的 56 项陈述列表。确定了四个主要主题:(一)虚弱筛查原则,(二)实际情况和后勤,(三)虚弱领域和(四)虚弱危险因素。
在第一轮中,接受了 56 项陈述中的 13 项(23%)。在收到反馈后,创建了 22 项新陈述并在第二轮(2021 年 10 月)重新循环使用。其中,最终接受了 19 项(54%)。达成的共识是,理想的虚弱筛查应简短(<5 分钟)、多维且在虚弱谱内具有良好校准,反映就诊前 2-4 周的基线状态。筛查应理想地成为常规、迅速(抵达后<4 小时)并在 ED 首次接触时完成。确定功能能力、移动能力、认知、药物使用和社会因素为纳入理想筛查的最重要变量。
尽管在 ED 中虚弱筛查的重要要求和理想筛查中应包括的变量方面达成了明确共识,但仍需要更多的研究来将筛查付诸于临床实践。