寻找虚弱的操作性定义：基于德尔菲法的共识声明：虚弱操作性定义共识会议项目。
Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project.
机构信息
Hospital Universitario de Getafe, Madrid, Spain.
出版信息
J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):62-7. doi: 10.1093/gerona/gls119. Epub 2012 Apr 16.
Abstract
BACKGROUND
There is no consensus regarding the definition of frailty for clinical uses.
METHODS
A modified Delphi process was used to attempt to achieve consensus definition. Experts were selected from different fields and organized into five Focus Groups. A questionnaire was developed and sent to experts in the area of frailty. Responses and comments were analyzed using a pre-established strategy. Statements with an agreement more than or equal to 80% were accepted.
RESULTS
Overall, 44% of the statements regarding the concept of frailty and 18% of the statements regarding diagnostic criteria were accepted. There was consensus on the value of screening for frailty and about the identification of six domains of frailty for inclusion in a clinical definition, but no agreement was reached concerning a specific set of clinical/laboratory biomarkers useful for diagnosis.
CONCLUSIONS
There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions. However, additional research is needed before an operative definition of frailty can be established.
摘要
背景
目前，临床上还没有关于衰弱的统一定义。
方法
采用改良 Delphi 法试图达成共识性定义。专家来自不同领域，分为五个焦点小组。制定问卷并发送给衰弱领域的专家。使用既定策略分析回复和意见。若意见超过或等于 80%，则予以采纳。
结果
衰弱概念相关的表述中有 44%，衰弱诊断标准相关的表述中有 18%，这两部分的表述内容最终被采纳。对于衰弱的筛查具有临床意义，以及纳入临床定义的衰弱 6 个领域的鉴定，专家们达成了共识，但对于用于诊断的特定临床/实验室生物标志物组，没有达成一致意见。
结论
专家们对于在临床环境中定义衰弱的有用性以及其主要维度表示认可。然而，在建立衰弱的操作性定义之前，还需要开展更多的研究。
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