Bo Li, Xiaojiong Du
Department of Vascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
Front Cardiovasc Med. 2024 Feb 2;11:1329863. doi: 10.3389/fcvm.2024.1329863. eCollection 2024.
Non-traumatic lower limb ischemic diseases are extremely rare among young people. Clinically, they are mainly seen in the form of popliteal artery entrapment syndrome (PAES). In addition, with the prevalence of COVID-19 infection, more and more studies report that COVID-19 infection may lead to arteriovenous thrombosis, which could cause lower limb ischemia. This case reported that a 31-year-old male amateur football player who developed intermittent claudication after recovering from COVID-19. After 2 months of consultation, he was ultimately diagnosed with PAES. As is well known, PAES is mostly caused by long-term compression of the popliteal artery by abnormal anatomical structures, resulting in thickening of the vascular outer membrane and progression of the disease until intimal damage and thrombosis, leading to lower limb ischemia. During the progression of the disease, there may be multiple factors that accelerate its progression. Therefore, combined with the patient's clinical history and related studies on confirmed thrombosis caused by COVID-19, we can infer that COVID-19 could accelerate the occurrence of PAES.
非创伤性下肢缺血性疾病在年轻人中极为罕见。临床上，它们主要以腘动脉受压综合征（PAES）的形式出现。此外，随着新冠病毒感染的流行，越来越多的研究报告称，新冠病毒感染可能导致动静脉血栓形成，进而引起下肢缺血。本病例报告了一名31岁的男性业余足球运动员，在新冠病毒感染康复后出现间歇性跛行。经过2个月的会诊，他最终被诊断为PAES。众所周知，PAES主要是由异常解剖结构对腘动脉的长期压迫引起的，导致血管外膜增厚，病情进展直至内膜损伤和血栓形成，从而导致下肢缺血。在疾病进展过程中，可能有多种因素加速其进展。因此，结合患者的临床病史以及关于新冠病毒感染导致确诊血栓形成的相关研究，我们可以推断新冠病毒可能加速PAES的发生。
