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右大脑中动脉卒中患者的异己手综合征揭秘

Alien Hand Syndrome Unveiled in a Patient With Right Middle Cerebral Artery Stroke.

作者信息

Rashwan Ghada, Elagha Sara, Aldaham Tahani, Thomas Liza

机构信息

Internal Medicine, Rashid Hospital, Dubai Academic Health Corporation, Dubai, ARE.

出版信息

Cureus. 2024 Jan 19;16(1):e52552. doi: 10.7759/cureus.52552. eCollection 2024 Jan.

DOI:10.7759/cureus.52552
PMID:38371035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10874505/
Abstract

Alien hand syndrome (AHS) is a rare but significant disorder, characterized by involuntary and often complex movements of one's hand. These movements seem to occur independently and unconsciously, separate from a person's intended actions.  We report a case of a 70-year-old male who presented to the emergency department with left sided hemiplegia following a stroke in the right middle cerebral artery (MCA) that affected the right temporal, parietal and internal capsule region. Upon additional inquiry, the patient reported experiencing involuntary, abrupt movements in his left upper and lower limbs particularly while attempting voluntary movements. As per the patient, these symptoms occurred prior to the onset of limb weakness. The diagnosis of AHS was made after excluding other differentials based on the clinical, metabolic and radiological picture.  Our patient exhibited unique symptoms and had a different presentation from that mentioned in the literature, as the onset of symptoms preceded the development of limb weakness typically associated with stroke. Involvement of the upper and lower limb and onset of symptoms prior to limb weakness make this case exceptionally rare. Moreover, acknowledging alien hand/limb syndrome as a distinct condition, separate from the broad category of post-stroke movement disorder, carries significant implications for both the management and prognosis of affected individuals.

摘要

异己手综合征(AHS)是一种罕见但严重的疾病,其特征是手部出现不自主且往往复杂的运动。这些运动似乎独立且无意识地发生,与个人的意图动作无关。我们报告一例70岁男性患者,因右侧大脑中动脉(MCA)卒中导致右侧颞叶、顶叶和内囊区域梗死,出现左侧偏瘫而就诊于急诊科。经进一步询问,患者报告其左上肢和下肢出现不自主、突发运动,尤其是在尝试自主运动时。据患者描述,这些症状在肢体无力发作之前就已出现。在根据临床、代谢和影像学表现排除其他鉴别诊断后,确诊为异己手综合征。我们的患者表现出独特的症状,与文献中所述的表现不同,因为症状发作先于通常与卒中相关的肢体无力的发展。上肢和下肢均受累且症状在肢体无力之前发作,使得该病例极为罕见。此外,认识到异己手/肢体综合征是一种与广泛的卒中后运动障碍不同的独特疾病,对受影响个体的管理和预后具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93b9/10874505/572f119dffb8/cureus-0016-00000052552-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93b9/10874505/588c224527ec/cureus-0016-00000052552-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93b9/10874505/b91dcc5a7402/cureus-0016-00000052552-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93b9/10874505/572f119dffb8/cureus-0016-00000052552-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93b9/10874505/588c224527ec/cureus-0016-00000052552-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93b9/10874505/b91dcc5a7402/cureus-0016-00000052552-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93b9/10874505/572f119dffb8/cureus-0016-00000052552-i03.jpg

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本文引用的文献

1
An Investigation on the Preconditions and Diagnosis Methods for Alien Hand Syndrome.异己手综合征的前提条件及诊断方法研究
Cureus. 2022 Feb 19;14(2):e22381. doi: 10.7759/cureus.22381. eCollection 2022 Feb.
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Alien Leg Syndrome in Two Cases of Corticobasal Syndrome.两例皮质基底节综合征患者出现异己腿综合征
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Alien hand syndrome - a rare presentation of stroke.异己手综合征——一种罕见的中风表现。
J Community Hosp Intern Med Perspect. 2020 May 21;10(2):149-150. doi: 10.1080/20009666.2020.1756610.
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Paroxysmal posterior variant alien hand syndrome associated with parietal lobe infarction: case presentation.与顶叶梗死相关的阵发性后变异型异手综合征:病例报告
Cogn Neurodyn. 2016 Oct;10(5):453-5. doi: 10.1007/s11571-016-9388-y. Epub 2016 Apr 28.
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Alien hand and leg as the presenting feature of probable sporadic Creutzfeldt-Jakob disease: A rare presentation of a rare disease.异己手和腿作为可能的散发性克雅氏病的首发特征:一种罕见疾病的罕见表现。
Ann Indian Acad Neurol. 2015 Jan-Mar;18(1):99-102. doi: 10.4103/0972-2327.144278.
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Pathophysiology and treatment of alien hand syndrome.异己手综合征的病理生理学与治疗
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Callosal disconnection syndrome after corpus callosum infarct: a diffusion tensor tractography study.胼胝体梗死后胼胝体切断综合征:一项弥散张量纤维束成像研究。
J Stroke Cerebrovasc Dis. 2013 Oct;22(7):e240-4. doi: 10.1016/j.jstrokecerebrovasdis.2012.10.015. Epub 2012 Dec 12.
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The biophysical bases of will-less behaviors.意志缺失行为的生物物理基础。
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