Thananjeyan Akshaya Lakshmi, Siu Anna, Jennings Angela, Bala Chandra
Emergency Department, St. Vincent's Hospital, Sydney, NSW, Australia.
Personal-Eyes, Sydney, NSW, Australia.
Clin Ophthalmol. 2024 Feb 13;18:451-458. doi: 10.2147/OPTH.S442931. eCollection 2024.
To assess visual outcomes of the implantation of a non-diffractive extended depth of focus (EDOF) intraocular lens (IOL) in patients with age-related macular degeneration (AMD).
Ophthalmology practice, Sydney, Australia.
Retrospective chart review.
Patients with AMD undergoing cataract surgery and receiving non-diffractive EDOF AcrySof IQ Vivity IOL implantation over a 2-year period were identified. Corrected distance visual acuity (CDVA), distance-corrected near visual acuity (DCNVA; 50 cm), contrast sensitivity, central foveal thickness, VF-14 questionnaire results, and quality of life where available were analyzed.
A total of 28 sequential patients (51 eyes) were included in this pilot study (46% male, mean age 77.4 years). Of 27 eyes that had late AMD, 17 (63%) had wet AMD. Mean patient preoperative CDVA was logMAR 0.32±0.29. Postoperative monocular CDVA and DCNVA were logMAR 0.20±0.25 and N9±5 (range N5-N36), respectively. Eyes achieving postoperative CDVA of Snellen 6/5-6/12 (n=42, 82%), 6/15-6/24 (n=7, 14%), and greater than 6/24 (n=2, 4%) achieved a mean DCNVA of N8 (range N5-N10), N13 (range N10-N18), and N27 (range N18-N36), respectively. Eyes achieving CDVA of Snellen 6/5-6/12 showed contrast sensitivity within the normal range. On postoperative VF-14 questionnaire, patients with CDVA of Snellen 6/5-6/12 reported minimal visual impairment, while patients with CDVA greater than 6/15 reported mild impairment. A majority of patients (96%, n=27) were satisfied with the improvement in quality of life postoperatively. No intraoperative complications were reported.
The EDOF AcrySof IQ Vivity IOL provides improved near vision proportional to distance vision in patients with early AMD.
评估非衍射型扩展景深（EDOF）人工晶状体（IOL）植入年龄相关性黄斑变性（AMD）患者后的视觉效果。
澳大利亚悉尼的眼科诊所。
回顾性病历审查。
确定在2年期间接受白内障手术并植入非衍射型EDOF AcrySof IQ Vivity IOL的AMD患者。分析矫正远视力（CDVA）、距离矫正近视力（DCNVA；50 cm）、对比敏感度、中央凹厚度、VF-14问卷结果以及可获得的生活质量。
本前瞻性研究共纳入28例连续患者（51只眼）（男性占46%，平均年龄77.4岁）。在27只患有晚期AMD的眼中，17只（63%）为湿性AMD。患者术前平均CDVA为logMAR 0.32±0.29。术后单眼CDVA和DCNVA分别为logMAR 0.20±0.25和N9±5（范围N5 - N36）。术后CDVA达到Snellen 6/5 - 6/12（n = 42，82%）、6/15 - 6/24（n = 7，14%）和大于6/24（n = 2，4%）的眼，其平均DCNVA分别为N8（范围N5 - N10）、N13（范围N10 - N18）和N27（范围N18 - N36）。CDVA达到Snellen 6/5 - 6/12的眼对比敏感度在正常范围内。在术后VF-14问卷中，CDVA为Snellen 6/5 - 6/12的患者报告视觉损害最小，而CDVA大于6/15的患者报告有轻度损害。大多数患者（96%，n = 27）对术后生活质量的改善感到满意。未报告术中并发症。
EDOF AcrySof IQ Vivity IOL在早期AMD患者中提供了与远视力成比例的近视力改善。
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