Zhang Wuxia, Chen Yupeng
Department of Biomedical Engineering, University of Connecticut, Storrs, CT, United States.
Front Chem. 2024 Jan 18;11:1346014. doi: 10.3389/fchem.2023.1346014. eCollection 2023.
Janus base nanotubes are novel, self-assembled nanomaterials. Their original designs were inspired by DNA base pairs, and today a variety of chemistries has developed, distinguishing them as a new family of materials separate from DNA origami, carbon nanotubes, polymers, and lipids. This review article covers the principal examples of self-assembled Janus base nanotubes, which are driven by hydrogen-bond and π-π stacking interactions in aqueous environments. Specifically, self-complementary hydrogen bonds organize molecules into ordered arrays, forming macrocycles, while π-π interactions stack these structures to create tubular forms. This review elucidates the molecular interactions that govern the assembly of nanotubes and advances our understanding of nanoscale self-assembly in water.
Janus碱基纳米管是新型的自组装纳米材料。它们最初的设计灵感来源于DNA碱基对，如今已经发展出了多种化学结构，使其成为一个与DNA折纸、碳纳米管、聚合物和脂质不同的新型材料家族。这篇综述文章涵盖了自组装Janus碱基纳米管的主要实例，这些纳米管在水性环境中由氢键和π-π堆积相互作用驱动。具体而言，自互补氢键将分子组织成有序阵列，形成大环，而π-π相互作用将这些结构堆叠起来以形成管状结构。这篇综述阐明了控制纳米管组装的分子相互作用，并增进了我们对水中纳米级自组装的理解。
