信守承诺：对微剂量研究现状的批判
Keeping the promise: a critique of the current state of microdosing research.
作者信息
Petranker Rotem, Anderson Thomas, Fewster Emily C, Aberman Youval, Hazan Marik, Gaffrey Michael, Seli Paul
机构信息
Department of Psychology, Neuroscience and Behaviour, Hamilton, ON, Canada.
Department of Psychology, University of Toronto, Toronto, ON, Canada.
出版信息
Front Psychiatry. 2024 Feb 5;15:1217102. doi: 10.3389/fpsyt.2024.1217102. eCollection 2024.
INTRODUCTION
The practice of taking small, sub-hallucinogenic doses of psychedelics, known as microdosing, has exploded in popularity over the last decade. Users claim benefits ranging from improved mood and enhanced creativity to an increased sense of meaning and connectedness in life. While research on microdosing is still lagging behind the shift in public opinion, several papers have been published in the last five years which attempted to assess the effects of microdosing.
METHODS
This review paper aimed to critically analyze the research practices used in the recent wave of microdosing research: We reviewed 15 papers published before the closing date of this review in March 2022.
RESULTS
Our review concludes that it is premature to draw any conclusions about the efficacy or safety of microdosing since the research quality cannot be considered confirmatory.
DISCUSSION
We propose some potential causes for the current state of the literature and some suggestions for how these causes may be ameliorated.
引言
服用小剂量、低于致幻剂量的迷幻剂，即所谓的微剂量服用，在过去十年中人气急剧上升。使用者声称其益处包括改善情绪、增强创造力，以及提升生活中的意义感和联系感。尽管关于微剂量服用的研究仍滞后于公众舆论的转变，但在过去五年里已有几篇论文发表，试图评估微剂量服用的效果。
方法
这篇综述论文旨在批判性地分析最近一波微剂量服用研究中所采用的研究方法：我们回顾了在本综述于2022年3月截止日期前发表的15篇论文。
结果
我们的综述得出结论，由于研究质量不能被视为具有确定性，因此就微剂量服用的疗效或安全性得出任何结论都为时过早。
讨论
我们提出了造成当前文献状况的一些潜在原因，以及关于如何改善这些原因的一些建议。
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