Chorzelski T P, Rogozinski T, Sulej J
J Cutan Pathol. 1979 Apr;6(2):130-3. doi: 10.1111/j.1600-0560.1979.tb01114.x.
Explants of skin from patients with pemphigus vulgaris and pemphigus foliaceus taken in the active stages of the disease had in vivo bound IgG in the intercellular area. After 24-48 h incubation of these explants in normal sera acantholytic bullae developed above the stratum basale, thus indicating that the bound IgG is probably in vivo bound pemphigus antibody. In both cases, skin from the inactive stage of the disease contained no in vivo bound pemphigus antibodies. Explants of these skin specimens failed to develop acantholysis in culture.
寻常型天疱疮和落叶型天疱疮患者在疾病活动期所取的皮肤外植体，在细胞间区域有体内结合的IgG。将这些外植体在正常血清中孵育24 - 48小时后，在基底细胞层上方形成棘层松解性水疱，这表明结合的IgG可能是体内结合的天疱疮抗体。在这两种情况下，疾病非活动期的皮肤均未含有体内结合的天疱疮抗体。这些皮肤标本的外植体在培养中未发生棘层松解。
