Anupong Suparinthon, Chadsuthi Sudarat, Hongsing Parichart, Hurst Cameron, Phattharapornjaroen Phatthranit, Rad S M Ali Hosseini, Fernandez Stefan, Huang Angkana T, Vatanaprasan Porames, Saethang Thammakorn, Luk-In Sirirat, Storer Robin James, Ounjai Puey, Devanga Ragupathi Naveen Kumar, Kanthawee Phitsanuruk, Ngamwongsatit Natharin, Badavath Vishnu Nayak, Thuptimdang Wanwara, Leelahavanichkul Asada, Kanjanabuch Talerngsak, Miyanaga Kazuhiko, Cui Longzhu, Nanbo Asuka, Shibuya Kenji, Kupwiwat Rosalyn, Sano Daisuke, Furukawa Takashi, Sei Kazunari, Higgins Paul G, Kicic Anthony, Singer Andrew C, Chatsuwan Tanittha, Trowsdale Sam, Abe Shuichi, Ishikawa Hitoshi, Amarasiri Mohan, Modchang Charin, Wannigama Dhammika Leshan
Biophysics Group, Department of Physics, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Department of Physics, Faculty of Science, Naresuan University, Phitsanulok 65000, Thailand.
iScience. 2024 Jan 26;27(3):109043. doi: 10.1016/j.isci.2024.109043. eCollection 2024 Mar 15.
This study investigated the potential of using SARS-CoV-2 viral concentrations in dust as an additional surveillance tool for early detection and monitoring of COVID-19 transmission. Dust samples were collected from 8 public locations in 16 districts of Bangkok, Thailand, from June to August 2021. SARS-CoV-2 RNA concentrations in dust were quantified, and their correlation with community case incidence was assessed. Our findings revealed a positive correlation between viral concentrations detected in dust and the relative risk of COVID-19. The highest risk was observed with no delay (0-day lag), and this risk gradually decreased as the lag time increased. We observed an overall decline in viral concentrations in public places during lockdown, closely associated with reduced human mobility. The effective reproduction number for COVID-19 transmission remained above one throughout the study period, suggesting that transmission may persist in locations beyond public areas even after the lockdown measures were in place.
本研究调查了将尘埃中严重急性呼吸综合征冠状病毒2（SARS-CoV-2）病毒浓度用作早期检测和监测2019冠状病毒病（COVID-19）传播的额外监测工具的潜力。2021年6月至8月期间，从泰国曼谷16个区的8个公共场所采集了灰尘样本。对灰尘中的SARS-CoV-2 RNA浓度进行了定量，并评估了它们与社区病例发病率的相关性。我们的研究结果显示，尘埃中检测到的病毒浓度与COVID-19的相对风险呈正相关。在无延迟（0天滞后）时观察到最高风险，并且随着滞后时间的增加，这种风险逐渐降低。我们观察到封锁期间公共场所的病毒浓度总体下降，这与人类流动性降低密切相关。在整个研究期间，COVID-19传播的有效再生数保持在1以上，这表明即使在实施封锁措施后，传播可能在公共区域以外的地方持续存在。
