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在癌症患者人群中 COVID-19 大流行期间异常尿液药物检测的流行率:回顾性研究。

Prevalence of abnormal urine drug tests during COVID-19 pandemic in the cancer patient population: retrospective study.

机构信息

Department of Pain Medicine, Division of Anesthesiology, Critical Care Medicine & Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Department of Physical Medicine & Rehabilitation, Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

Pain Manag. 2024 Mar;14(3):129-138. doi: 10.2217/pmt-2023-0122. Epub 2024 Feb 20.

Abstract

Opioid misuse is a persistent concern, heightened by the COVID-19 pandemic. This study examines the risk factors contributing to elevated rates of abnormal urine drug tests (UDTs) in the cancer pain patient population during COVID-19. A retrospective chart review of 500 patient encounters involving UDTs at a comprehensive cancer center. Medication adherence rates increase when UDTs are incorporated into a chronic cancer pain management protocol. Higher positive tests for illicit or nonprescribed substances in patients with specific risk factors: current smokers (tobacco), no active cancer and concurrent benzodiazepine use. This research emphasizes the increased risk of opioid misuse during COVID-19 among cancer pain patients with specific risk factors outlined in the results.

摘要

阿片类药物滥用是一个持续存在的问题,尤其是在 COVID-19 大流行期间。本研究旨在探讨导致癌症疼痛患者在 COVID-19 期间异常尿液药物检测(UDT)率升高的相关因素。对一家综合性癌症中心的 500 例 UDT 患者就诊情况进行了回顾性图表审查。UDT 纳入慢性癌症疼痛管理方案时,药物依从性会提高。具有特定风险因素的患者中,非法或非处方物质的阳性检测率更高:当前吸烟者(烟草)、无活动性癌症且同时使用苯二氮䓬类药物。该研究强调了 COVID-19 期间癌症疼痛患者中具有特定风险因素的患者(如上述结果所列出的)存在阿片类药物滥用风险增加的问题。

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