Powner Michael B, Jeffery Glen
Department of Optometry and Visual Science, Centre for Applied Vision Research, School of Health and Psychological Sciences, City, University of London, London, UK.
Department of Visual Neuroscience, UCL Institute of Ophthalmology, University College London, London, UK.
J Biophotonics. 2024 May;17(5):e202300521. doi: 10.1002/jbio.202300521. Epub 2024 Feb 20.
Mitochondria regulate metabolism, but solar light influences its rate. Photobiomodulation (PBM) with red light (670 nm) increases mitochondrial membrane potentials and adenosine triphosphate production and may increase glucose demand. Here we show, with a glucose tolerance test, that PBM of normal subjects significantly reduces blood sugar levels. A 15 min exposure to 670 nm light reduced the degree of blood glucose elevation following glucose intake by 27.7%, integrated over 2 h after the glucose challenge. Maximum glucose spiking was reduced by 7.5%. Consequently, PBM with 670 nm light can be used to reduce blood glucose spikes following meals. This intervention may reduce damaging fluctuations of blood glucose on the body.
线粒体调节新陈代谢，但太阳光会影响其速率。用红光（670纳米）进行光生物调节（PBM）可增加线粒体膜电位和三磷酸腺苷的产生，并可能增加葡萄糖需求。在此我们通过葡萄糖耐量试验表明，对正常受试者进行PBM可显著降低血糖水平。在葡萄糖激发后2小时内，暴露于670纳米光15分钟可使摄入葡萄糖后血糖升高程度降低27.7%。最大血糖峰值降低了7.5%。因此，用670纳米光进行PBM可用于减少餐后血糖峰值。这种干预可能会减少血糖对身体造成损害的波动。
