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75 岁及以上、有高住院风险人群的住院原因和累积死亡率:一项前瞻性研究。

Reasons for hospitalisation and cumulative mortality in people, 75 years or older, at high risk of hospital admission: a prospective study.

机构信息

Primary Health Care Centre Finspång, Finspång, Sweden.

Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.

出版信息

BMC Geriatr. 2024 Feb 20;24(1):176. doi: 10.1186/s12877-024-04771-2.

Abstract

BACKGROUND

A small proportion of the older population accounts for a high proportion of healthcare use. For effective use of limited healthcare resources, it is important to identify the group with greatest needs. The aim of this study was to explore frequency and reason for hospitalisation and cumulative mortality, in an older population at predicted high risk of hospital admission, and to assess if a prediction model can be used to identify individuals with the greatest healthcare needs. Furthermore, discharge diagnoses were explored to investigate if they can be used as basis for specific interventions in the high-risk group.

METHODS

All residents, 75 years or older, living in Östergötland, Sweden, on January 1, 2017, were included. Healthcare data from 2016 was gathered and used by a validated prediction model to create risk scores for hospital admission. The population was then divided into groups by percentiles of risk. Using healthcare data from 2017-2018, two-year cumulative incidence of hospitalisation was analysed using Gray´s test. Cumulative mortality was analysed with the Kaplan-Meier method and primary discharge diagnoses were analysed with standardised residuals.

RESULTS

Forty thousand six hundred eighteen individuals were identified (mean age 82 years, 57.8% women). The cumulative incidence of hospitalisation increased with increasing risk of hospital admission (24% for percentiles < 60 to 66% for percentiles 95-100). The cumulative mortality also increased with increasing risk (7% for percentiles < 60 to 43% for percentiles 95-100). The most frequent primary discharge diagnoses for the population were heart diseases, respiratory infections, and hip injuries. The incidence was significantly higher for heart diseases and respiratory infections and significantly lower for hip injuries, for the population with the highest risk of hospital admission (percentiles 85-100).

CONCLUSIONS

Individuals 75 years or older, with high risk of hospital admission, were demonstrated to have considerable higher cumulative mortality as well as incidence of hospitalisation. The results support the use of the prediction model to direct resources towards individuals with highest risk scores, and thus, likely the greatest care needs. There were only small differences in discharge diagnoses between the risk groups, indicating that interventions to reduce hospitalisations should be personalised.

TRIAL REGISTRATION

clinicaltrials.gov Identifier: NCT03180606, first posted 08/06/2017.

摘要

背景

一小部分老年人占据了大量的医疗保健使用量。为了有效利用有限的医疗保健资源,确定需求最大的群体非常重要。本研究旨在探讨在预计有较高住院风险的老年人群中,住院频率和原因以及累积死亡率,并评估预测模型是否可用于识别最需要医疗保健的个体。此外,还探讨了出院诊断是否可作为高危人群特定干预措施的基础。

方法

所有居住在瑞典延雪平省,年龄在 2017 年 1 月 1 日为 75 岁或以上的居民均被纳入研究。2016 年的医疗保健数据通过验证的预测模型进行收集,以创建住院风险评分。然后,根据风险得分的百分比将人群分为不同的组。使用 2017-2018 年的医疗保健数据,采用 Gray 检验分析两年累积住院发生率。采用 Kaplan-Meier 方法分析累积死亡率,采用标准化残差分析主要出院诊断。

结果

共确定了 4618 名患者(平均年龄 82 岁,57.8%为女性)。随着住院风险的增加,住院累积发生率也随之增加(风险得分处于 60%至 100%分位的人群累积发生率为 24%,而处于 10%至 60%分位的人群累积发生率为 66%)。随着风险的增加,累积死亡率也随之增加(风险得分处于 60%至 100%分位的人群累积死亡率为 7%,而处于 10%至 60%分位的人群累积死亡率为 43%)。对于该人群,最常见的主要出院诊断为心脏病、呼吸道感染和髋部损伤。对于有最高住院风险(85%至 100%分位)的人群,心脏病和呼吸道感染的发病率明显较高,而髋部损伤的发病率明显较低。

结论

年龄在 75 岁或以上、有较高住院风险的个体,其累积死亡率和住院发生率均显著较高。结果支持使用预测模型将资源投向风险评分最高的个体,因此,可能是最需要护理的个体。风险组之间的出院诊断差异较小,表明应针对减少住院人数的干预措施进行个性化设置。

试验注册

clinicaltrials.gov 标识符:NCT03180606,首次注册日期为 2017 年 8 月 6 日。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ee/10877827/714326f0a52c/12877_2024_4771_Fig1_HTML.jpg

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