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纳米医学在根除方面的应用:最新进展、挑战与未来展望。

Nanomedicine for the eradication of : recent advances, challenges and future perspective.

机构信息

Department of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, 110062, India.

Centre for Translational & Clinical Research, School of Chemical & Life Sciences, Jamia Hamdard, New Delhi, 110062, India.

出版信息

Future Microbiol. 2024 Mar;19:431-447. doi: 10.2217/fmb-2023-0189. Epub 2024 Feb 21.

DOI:10.2217/fmb-2023-0189
Abstract

infection is linked to gastritis, ulcers and gastric cancer. Nanomedicine offers a promising solution by utilizing nanoparticles for precise drug delivery, countering antibiotic resistance and delivery issues. Nanocarriers such as liposomes and nanoparticles enhance drug stability and circulation, targeting infection sites through gastric mucosa characteristics. Challenges include biocompatibility, stability, scalability and personalized therapies. Despite obstacles, nanomedicine's potential for reshaping eradication is significant and showcased in this review focusing on benefits, limitations and future prospects of nanomedicine-based strategies.

摘要

感染与胃炎、溃疡和胃癌有关。纳米医学通过利用纳米颗粒进行精确的药物输送,对抗抗生素耐药性和输送问题,提供了有希望的解决方案。纳米载体如脂质体和纳米颗粒增强了药物的稳定性和循环,通过胃黏膜的特性靶向感染部位。挑战包括生物相容性、稳定性、可扩展性和个性化治疗。尽管存在障碍,但纳米医学在重新塑造根除策略方面的潜力是巨大的,本综述重点介绍了基于纳米医学的策略的益处、局限性和未来前景。

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引用本文的文献

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Application of Nanodrug Delivery Systems in Enhancing Treatment of Gastritis and Gastric Cancer: A Systematic Evaluation of Targeted Therapy.纳米药物递送系统在增强胃炎和胃癌治疗中的应用:靶向治疗的系统评价
Pharmaceutics. 2025 May 22;17(6):683. doi: 10.3390/pharmaceutics17060683.
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Anti-urease therapy: a targeted approach to mitigating antibiotic resistance in Helicobacter pylori while preserving the gut microflora.抗脲酶疗法:一种在保留肠道微生物群的同时减轻幽门螺杆菌抗生素耐药性的靶向方法。
Gut Pathog. 2025 May 28;17(1):37. doi: 10.1186/s13099-025-00708-1.
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Infection in Patients with Gastric Cancer: A 2024 Update.
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