Starting the journey: Understanding the roles of complement proteins in liver diseases through mendelian randomization.
作者信息
Rezaee-Zavareh Mohammad Saeid, Kim Naomy, Yang Ju Dong
机构信息
Middle East Liver Diseases Center, Tehran, Iran.
Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
出版信息
Clin Mol Hepatol. 2024 Apr;30(2):150-153. doi: 10.3350/cmh.2024.0116. Epub 2024 Feb 22.
Abstract
摘要
相似文献
1
Starting the journey: Understanding the roles of complement proteins in liver diseases through mendelian randomization.开启征程：通过孟德尔随机化理解补体蛋白在肝脏疾病中的作用
Clin Mol Hepatol. 2024 Apr;30(2):150-153. doi: 10.3350/cmh.2024.0116. Epub 2024 Feb 22.
2
Correspondence to editorial on "Protein-centric omics analysis reveals circulating complements linked to non-viral liver diseases as potential therapeutic targets".致关于“以蛋白质为中心的组学分析揭示与非病毒性肝病相关的循环补体作为潜在治疗靶点”的社论的信函。
Clin Mol Hepatol. 2024 Oct;30(4):987-988. doi: 10.3350/cmh.2024.0266. Epub 2024 Apr 19.
3
Causal relationships between metabolic-associated fatty liver disease and iron status: Two-sample Mendelian randomization.代谢相关脂肪性肝病与铁状态之间的因果关系：两样本孟德尔随机化研究。
Liver Int. 2022 Dec;42(12):2759-2768. doi: 10.1111/liv.15455. Epub 2022 Oct 28.
4
An introduction to Mendelian randomization with applications in neurology.孟德尔随机化方法及其在神经病学中的应用简介。
Mult Scler Relat Disord. 2018 Aug;24:72-78. doi: 10.1016/j.msard.2018.06.017. Epub 2018 Jun 20.
5
Causal relationship between air pollution, lung function, gastroesophageal reflux disease, and non-alcoholic fatty liver disease: univariate and multivariate Mendelian randomization study.空气污染、肺功能、胃食管反流病和非酒精性脂肪性肝病之间的因果关系：单变量和多变量孟德尔随机化研究。
Front Public Health. 2024 Apr 29;12:1368483. doi: 10.3389/fpubh.2024.1368483. eCollection 2024.
6
Mendelian randomization: how genetics is pushing the boundaries of epidemiology to identify new causes of heart disease.孟德尔随机化：遗传学如何推动流行病学的边界，以确定心脏病的新病因。
Can J Cardiol. 2013 Jan;29(1):30-6. doi: 10.1016/j.cjca.2012.09.014. Epub 2012 Nov 29.
7
Investigating Causal Relations between Genetic-Related Intermediate Endophenotype and Risk of Chronic Prostatitis: Mendelian Randomization Study.探讨遗传相关中间表型与慢性前列腺炎发病风险之间的因果关系：孟德尔随机化研究。
Oxid Med Cell Longev. 2022 Aug 28;2022:4560609. doi: 10.1155/2022/4560609. eCollection 2022.
8
Genetic association and causal relationship between multiple modifiable risk factors and autoimmune liver disease: a two-sample mendelian randomization study.多可调节风险因素与自身免疫性肝病之间的遗传关联和因果关系：两样本孟德尔随机化研究。
J Transl Med. 2024 May 4;22(1):425. doi: 10.1186/s12967-024-05247-y.
9
Causal associations between platelet count, alcohol consumption, and the risk of liver hepatocellular carcinoma based on a Mendelian randomization study.基于孟德尔随机化研究的血小板计数、饮酒与肝癌风险之间的因果关系。
Front Endocrinol (Lausanne). 2024 May 22;15:1400573. doi: 10.3389/fendo.2024.1400573. eCollection 2024.
10
Causal associations between liver traits and Colorectal cancer: a Mendelian randomization study.肝脏特征与结直肠癌之间的因果关联：一项孟德尔随机化研究。
BMC Med Genomics. 2023 Dec 6;16(1):316. doi: 10.1186/s12920-023-01755-w.
引用本文的文献
1
Causal relationship and mediating role between depression and cognitive performance.抑郁与认知表现之间的因果关系及中介作用。
J Prev Alzheimers Dis. 2025 Sep;12(8):100196. doi: 10.1016/j.tjpad.2025.100196. Epub 2025 May 8.
2
Impact of Physical Activity on Overall Survival and Liver Cirrhosis Incidence in Steatotic Liver Disease: Insights from a Large Cohort Study Using Inverse Probability of Treatment Weighting.体力活动对非酒精性脂肪性肝病患者总体生存率和肝硬化发生率的影响：基于逆概率处理加权的大型队列研究的新认识
Nutrients. 2024 Aug 2;16(15):2532. doi: 10.3390/nu16152532.
3
Reassessing the Impact of Coffee Consumption on Liver Disease: Insights from a Large-Scale Cohort Study with IPTW Adjustment.重新评估咖啡消费对肝脏疾病的影响：基于 IPTW 调整的大规模队列研究的见解。
Nutrients. 2024 Jun 26;16(13):2020. doi: 10.3390/nu16132020.
4
Causal relationship between immune cells and hepatocellular carcinoma: a Mendelian randomisation study.免疫细胞与肝细胞癌之间的因果关系：一项孟德尔随机化研究
J Cancer. 2024 Jun 3;15(13):4219-4231. doi: 10.7150/jca.96744. eCollection 2024.
5
Reply to correspondence on "Protein-centric omics analysis reveals circulating complements linked to non-viral liver diseases as potential therapeutic targets".对关于“以蛋白质为中心的组学分析揭示与非病毒性肝病相关的循环补体作为潜在治疗靶点”的通信的回复
Clin Mol Hepatol. 2024 Oct;30(4):1037-1038. doi: 10.3350/cmh.2024.0320. Epub 2024 May 2.
6
Correspondence to editorial on "Protein-centric omics analysis reveals circulating complements linked to non-viral liver diseases as potential therapeutic targets".致关于“以蛋白质为中心的组学分析揭示与非病毒性肝病相关的循环补体作为潜在治疗靶点”的社论的信函。
Clin Mol Hepatol. 2024 Oct;30(4):987-988. doi: 10.3350/cmh.2024.0266. Epub 2024 Apr 19.
本文引用的文献
1
An integrative analysis of single-cell and bulk transcriptome and bidirectional mendelian randomization analysis identified C1Q as a novel stimulated risk gene for Atherosclerosis.单细胞和批量转录组的综合分析以及双向孟德尔随机化分析确定 C1Q 为动脉粥样硬化的一个新的刺激风险基因。
Front Immunol. 2023 Dec 21;14:1289223. doi: 10.3389/fimmu.2023.1289223. eCollection 2023.
2
Protein-centric omics analysis reveals circulating complements linked to non-viral liver diseases as potential therapeutic targets.以蛋白质为中心的组学分析揭示了与非病毒性肝病相关的循环补体作为潜在的治疗靶点。
Clin Mol Hepatol. 2024 Jan;30(1):80-97. doi: 10.3350/cmh.2023.0343. Epub 2023 Dec 7.
3
Complement C3 as a potential drug target in periodontitis: Evidence from the cis-Mendelian randomization approach.补体 C3 作为牙周炎的潜在药物靶点：来自顺式孟德尔随机化方法的证据。
J Clin Periodontol. 2024 Feb;51(2):127-134. doi: 10.1111/jcpe.13894. Epub 2023 Nov 5.
4
Mendelian randomization in hepatology: A review of principles, opportunities, and challenges.肝脏病学中的孟德尔随机化：原理、机遇与挑战综述
Hepatology. 2025 Jun 1;81(6):1836-1846. doi: 10.1097/HEP.0000000000000649. Epub 2023 Oct 24.
5
Integrating plasma proteomes with genome-wide association data for causal protein identification in multiple myeloma.将血浆蛋白质组与全基因组关联数据相结合，以鉴定多发性骨髓瘤中的因果蛋白质。
BMC Med. 2023 Sep 29;21(1):377. doi: 10.1186/s12916-023-03086-0.
6
Mendelian Randomization Analyses of Chronic Immune-Mediated Diseases, Circulating Inflammatory Biomarkers, and Cytokines in Relation to Liver Cancer.慢性免疫介导疾病、循环炎症生物标志物和细胞因子与肝癌关系的孟德尔随机化分析
Cancers (Basel). 2023 May 26;15(11):2930. doi: 10.3390/cancers15112930.
7
The Global Burden of Liver Disease.《全球肝脏疾病负担》
Clin Gastroenterol Hepatol. 2023 Jul;21(8):1978-1991. doi: 10.1016/j.cgh.2023.04.015. Epub 2023 Apr 28.
8
The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review.非酒精性脂肪性肝病（NAFLD）和非酒精性脂肪性肝炎（NASH）的全球流行病学：系统评价。
Hepatology. 2023 Apr 1;77(4):1335-1347. doi: 10.1097/HEP.0000000000000004. Epub 2023 Jan 3.
9
An update on the role of complement in hepatocellular carcinoma.补体在肝细胞癌中的作用研究进展。
Front Immunol. 2022 Oct 19;13:1007382. doi: 10.3389/fimmu.2022.1007382. eCollection 2022.
10
Investigating Causal Relations between Genetic-Related Intermediate Endophenotype and Risk of Chronic Prostatitis: Mendelian Randomization Study.探讨遗传相关中间表型与慢性前列腺炎发病风险之间的因果关系：孟德尔随机化研究。
Oxid Med Cell Longev. 2022 Aug 28;2022:4560609. doi: 10.1155/2022/4560609. eCollection 2022.
Zotero 插件