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在埃塞俄比亚南部的 Adare 综合医院就诊的糖尿病患者中的威胁视力的糖尿病视网膜病变及其预测因素:一项基于医院的横断面研究。

Sight-threatening diabetic retinopathy and its predictors among patients with diabetes visiting Adare General Hospital in Southern Ethiopia: a hospital-based cross-sectional study.

机构信息

Department of Ophthalmology and Optometry, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia

Department of Optometry, University of Gondar College of Medicine and Health Sciences, Gondar, Ethiopia.

出版信息

BMJ Open. 2024 Feb 21;14(2):e077552. doi: 10.1136/bmjopen-2023-077552.

DOI:10.1136/bmjopen-2023-077552
PMID:38387987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10882339/
Abstract

OBJECTIVE

The study aimed to determine the prevalence of sight-threatening diabetic retinopathy and its predictors among patients with diabetes attending Adare General Hospital in Southern Ethiopia.

DESIGN

A hospital-based cross-sectional study was conducted using a systematic random sampling method.

SETTING

The study was conducted at the diabetic clinic of Adare General Hospital in Sidama region, Southern Ethiopia.

PARTICIPANTS

The study included 391 patients with diabetes aged ≥18 years who had attended the diabetic clinic of Adare General Hospital in Southern Ethiopia.

MAIN OUTCOME MEASURES

Data were collected using questionnaires completed by an interviewer, a review of medical records and eye examinations.

RESULT

The study included 391 patients with diabetes with a median age of 49 years. The prevalence of sight-threatening diabetic retinopathy was 10.7% (95% CI: 7.7% to 14%). Rural dwellers (adjusted OR (AOR)=2.17, 95% CI: 1.05 to 4.46), duration of diabetes ≥6 years (AOR=2.43, 95% CI: 1.06 to 5.57), poor glycaemic control (AOR=2.80, 95% CI: 1.03 to 7.64), low physical activity (AOR=2.85, 95% CI: 1.01 to 8.05), hypertension (AOR=3.25, 95% CI: 1.48 to 7.15) and diabetic peripheral neuropathy (AOR=3.32, 95% CI: 1.18 to 9.33) were significantly associated with sight-threatening diabetic retinopathy.

CONCLUSION

This study showed a high prevalence of sight-threatening diabetic retinopathy. Sight-threatening diabetic retinopathy was significantly associated with modified factors such as glycaemic control, hypertension, physical activity and diabetic peripheral neuropathy. Therefore, all patients with diabetes were recommended to maintain normal blood glucose, avoid hypertension, exercise regularly and have regular eye examinations.

摘要

目的

本研究旨在确定在埃塞俄比亚南部阿代尔综合医院就诊的糖尿病患者中,威胁视力的糖尿病视网膜病变的患病率及其预测因素。

设计

采用系统随机抽样方法进行了一项基于医院的横断面研究。

地点

该研究在埃塞俄比亚南部希达玛地区阿代尔综合医院的糖尿病诊所进行。

参与者

该研究纳入了年龄≥18 岁、在埃塞俄比亚南部阿代尔综合医院糖尿病诊所就诊的 391 例糖尿病患者。

主要观察指标

数据通过访谈者完成的问卷、病历回顾和眼部检查收集。

结果

该研究纳入了 391 例中位年龄为 49 岁的糖尿病患者。威胁视力的糖尿病视网膜病变的患病率为 10.7%(95%CI:7.7%至 14%)。农村居民(校正比值比(AOR)=2.17,95%CI:1.05 至 4.46)、糖尿病病程≥6 年(AOR=2.43,95%CI:1.06 至 5.57)、血糖控制不佳(AOR=2.80,95%CI:1.03 至 7.64)、体力活动少(AOR=2.85,95%CI:1.01 至 8.05)、高血压(AOR=3.25,95%CI:1.48 至 7.15)和糖尿病周围神经病变(AOR=3.32,95%CI:1.18 至 9.33)与威胁视力的糖尿病视网膜病变显著相关。

结论

本研究显示威胁视力的糖尿病视网膜病变患病率较高。威胁视力的糖尿病视网膜病变与血糖控制、高血压、体力活动和糖尿病周围神经病变等改良因素显著相关。因此,建议所有糖尿病患者保持正常血糖,避免高血压,定期锻炼并定期进行眼部检查。

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