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格雷夫斯病中的胫前黏液性水肿:一例病例报告及文献治疗综述

Pretibial myxedema in Grave's disease: A case report and treatment review of the literature.

作者信息

Nguyen Van Bang, Nguyen Van Vy Hau, Van Le Chi, Linh Pham Nguyen Tuyen, Thi Xuan Nguyen, Vo Thanh Trang

机构信息

Center of Endocrinology and Diabetes Family Hospital Da Nang Vietnam.

Internal Medicine Department, Hue University of Medicine and Pharmacy Hue University Hue City Vietnam.

出版信息

Clin Case Rep. 2024 Feb 22;12(2):e8478. doi: 10.1002/ccr3.8478. eCollection 2024 Feb.

DOI:10.1002/ccr3.8478
PMID:38389965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10883341/
Abstract

KEY CLINICAL MESSAGE

Pretibial myxedema is a rare skin lesion in Grave's disease, which required topical glucocorticoid administration in long-term treatment. The patient's lesion has shrunk and become flatter than before treatment.

ABSTRACT

We present a case of biopsy-verified pretibial myxedema in a 70-year-old male patient with diagnosed hyperthyroidism and no prior history of Graves' disease. Topical corticosteroid and antithyroid drug administration led to successful resolution of the skin lesions. This case emphasizes the importance of considering pretibial myxedema even in atypical presentations of Graves' disease and underscores the value of prompt treatment.

摘要

关键临床信息

胫前黏液性水肿是格雷夫斯病中一种罕见的皮肤病变,长期治疗需要局部应用糖皮质激素。患者的病变已缩小,且比治疗前更平坦。

摘要

我们报告一例经活检证实的胫前黏液性水肿病例,患者为一名70岁男性,诊断为甲状腺功能亢进,既往无格雷夫斯病病史。局部应用皮质类固醇和抗甲状腺药物成功治愈了皮肤病变。该病例强调了即使在格雷夫斯病的非典型表现中也需考虑胫前黏液性水肿的重要性,并突出了及时治疗的价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6589/10883341/7abeba09440e/CCR3-12-e8478-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6589/10883341/6053d075329d/CCR3-12-e8478-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6589/10883341/7abeba09440e/CCR3-12-e8478-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6589/10883341/6053d075329d/CCR3-12-e8478-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6589/10883341/7abeba09440e/CCR3-12-e8478-g003.jpg

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Pretibial myxedema in Grave's disease: A case report and treatment review of the literature.格雷夫斯病中的胫前黏液性水肿:一例病例报告及文献治疗综述
Clin Case Rep. 2024 Feb 22;12(2):e8478. doi: 10.1002/ccr3.8478. eCollection 2024 Feb.
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Morphological Diversity of Pretibial Myxedema and Its Mechanism of Evolving Process and Outcome: A Retrospective Study of 216 Cases.胫前黏液性水肿的形态学多样性及其演变过程和结局机制:一项对216例患者的回顾性研究
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Pretibial myxedema: pathophysiology and treatment options.胫前黏液性水肿:病理生理学与治疗选择
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