一名甲状腺功能正常患者的胫前黏液性水肿：病例报告
Pretibial myxedema in a euthyroid patient: a case report.
作者信息
Ambachew Rediet, Yosef Tizita, Gebremariam Aklilu M, Demere Lishan, Aberra Theodros, Tarekegn Getahun, Reja Ahmed
机构信息
Department of Endocrinology, Addis Ababa University, College of health sciences, Addis Ababa, Ethiopia.
Department of Dermatology and Venereology, Addis Ababa University, College of health sciences, Addis Ababa, Ethiopia.
出版信息
Thyroid Res. 2021 Mar 1;14(1):4. doi: 10.1186/s13044-021-00096-z.
BACKGROUND
Pretibial myxedema also known as localized myxedema, thyroid dermopathy, or infiltrative dermopathy and rarely as localized mucinosis is an infrequent manifestation of Graves' disease. It can appear before, during, or after the thyrotoxic state. Euthyroid pretibial myxedema is a rare presentation with few case reports in the literature. This case highlights the importance of considering pretibial myxedema when characteristic skin lesions are observed in a euthyroid patient.
CASE PRESENTATION
A 72-year old male Ethiopian patient with a very rare presentation of biopsy-proven pretibial myxedema in a euthyroid state without history of thyroid disease and absence of thyroid autoimmune markers. Resolution of skin lesion was achieved after topical corticosteroid application.
CONCLUSION
Absence of history of thyroid disorder and normal thyroid function tests should not exclude the diagnosis of pretibial myxedema.
背景
胫前黏液性水肿也称为局限性黏液性水肿、甲状腺皮肤病变或浸润性皮肤病变，很少称为局限性黏液瘤病，是格雷夫斯病的一种罕见表现。它可出现在甲状腺毒症状态之前、期间或之后。甲状腺功能正常的胫前黏液性水肿是一种罕见的表现，文献中病例报告较少。该病例强调了在甲状腺功能正常的患者中观察到特征性皮肤病变时考虑胫前黏液性水肿的重要性。
病例介绍
一名72岁的埃塞俄比亚男性患者，表现非常罕见，经活检证实为甲状腺功能正常状态下的胫前黏液性水肿，无甲状腺疾病史且无甲状腺自身免疫标志物。局部应用皮质类固醇后皮肤病变得到缓解。
结论
无甲状腺疾病史且甲状腺功能检查正常不应排除胫前黏液性水肿的诊断。
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