Mahyuni Eka Lestari, Harahap Urip
Department of Occupational Safety and Health, Faculty of Public Health, Universitas Sumatera Utara, Medan, Indonesia.
Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.
J Adv Pharm Technol Res. 2024 Jan-Mar;15(1):56-61. doi: 10.4103/japtr.Japtr_388_23. Epub 2024 Jan 15.
Skin damage and aging are potential health problems for woman agriculture workers. This study aimed to test the efficacy of ethanol extract formulated in antiaging cream preparations as an aging treatment in women agriculture workers. The method carried out was an experimental study on woman agriculture workers who were willing to volunteer. The experimental scenario conducted related to the physical quality of antiaging cream products and the efficacy of creams on the skin as an antiaging treatment. Physical quality parameters of antiaging cream include organoleptic assessment, cream emulsion, homogeneity, viscosity, pH, distribution, and skin irritation test to evaluate potential side effects. Skin aging efficacy assessments were conducted on 12 subjects divided into four formula concentration groups. The physical skin identification parameters measured are moisture, pore size, pigmentation or spots, and wrinkles using a skin analyzer. The results found that leaf extract formulated as an antiaging cream can neutralize free radicals and is an effective countermeasure against premature skin aging. There were significant differences in the skin characteristics of woman agriculture workers who participated as samples. The formula with 5% concentrate and 7% extract of has provided a reaction and is more effective in continuous treatment. It provides skin moisture changes of more than 300%, disguises pore size and good pigmentation, and reduces wrinkles of farmers who are constantly exposed to chemicals and free radicals in their agricultural activities. The leaf extracts antiaging cream showed more significant changes in moisture and skin pigmentation. It was concluded that the use of leaf extract as the core ingredient of antiaging cream can be an innovation that is beneficial to the health of the farming community, especially among women agriculture workers.
皮肤损伤和老化是女性农业工人潜在的健康问题。本研究旨在测试配制在抗衰老面霜制剂中的乙醇提取物作为女性农业工人抗老化治疗方法的功效。所采用的方法是对愿意参与的女性农业工人进行实验研究。所进行的实验方案涉及抗衰老面霜产品的物理质量以及面霜对皮肤作为抗老化治疗的功效。抗衰老面霜的物理质量参数包括感官评估、乳膏乳液、均匀性、粘度、pH值、分布以及皮肤刺激性测试,以评估潜在的副作用。对12名受试者进行了皮肤老化功效评估,将其分为四个配方浓度组。使用皮肤分析仪测量的皮肤识别物理参数为水分、毛孔大小、色素沉着或斑点以及皱纹。结果发现,配制为抗衰老面霜的树叶提取物可以中和自由基,是对抗皮肤过早老化的有效对策。作为样本参与的女性农业工人的皮肤特征存在显著差异。含5%浓缩物和7%提取物的配方产生了反应,并且在持续治疗中更有效。它使皮肤水分变化超过300%,掩盖了毛孔大小并改善了色素沉着,减少了在农业活动中持续接触化学物质和自由基的农民的皱纹。树叶提取物抗衰老面霜在水分和皮肤色素沉着方面显示出更显著的变化。得出的结论是,使用树叶提取物作为抗衰老面霜的核心成分可能是一项有益于农业社区健康的创新,尤其是对女性农业工人而言。