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[口服疫苗根除脊髓灰质炎运动的失败:没有依从性就没有疫苗接种]

[Failure of poliomyelitis eradication campaign with oral vaccine: there's no vaccination without adherence].

作者信息

Seytre Bernard

机构信息

bnscommunication, 7 rue Ledion, 75014 Paris.

出版信息

Med Trop Sante Int. 2023 Nov 16;3(4). doi: 10.48327/mtsi.v3i4.2023.402. eCollection 2023 Dec 31.

Abstract

Thirty-five years after its launch, the Global Polio Eradication Initiative has yet to reach its original goal of 2000. Not only is the wild type 1 polio virus still endemic in two countries, but a new outbreak due to viruses derived from the live attenuated virus used for the oral vaccine has been spreading since 2016. The National Immunization Days (NID), during which teams go door-to-door and attract children to be vaccinated, have provoked violent opposition particularly in Northern Nigeria and in the area of India, Pakistan, Afghanistan. In both regions, the same rumor has developed that the vaccine contains sterilizing products, in order to limit the Muslim population. The organizers of the campaign multiplied in vain the NIDs to overcome the resistance, but pockets of insufficiently vaccinated population have persisted. This has allowed the wild virus to remain endemic and the new outbreak of vaccine-derived viruses to progress. We can wonder what the campaign would have become if its organizers had taken the time to reflect and reorient their strategy to rely on the routine vaccination of the Expanded Program on Immunization that does not arouse such opposition.

摘要

全球根除脊髓灰质炎行动发起35年后,仍未实现其2000年的最初目标。不仅野生1型脊髓灰质炎病毒在两个国家仍然流行,而且自2016年以来,由口服疫苗中使用的减毒活病毒衍生而来的病毒引发的新疫情一直在蔓延。全国免疫日期间,工作人员挨家挨户上门,吸引儿童接种疫苗,这引发了强烈反对,特别是在尼日利亚北部以及印度、巴基斯坦、阿富汗地区。在这两个地区,都出现了同样的谣言,称疫苗含有绝育成分,目的是限制穆斯林人口。该行动的组织者多次徒劳地增加全国免疫日,以克服阻力,但疫苗接种不足的人群仍然存在。这使得野生病毒得以继续流行,疫苗衍生病毒的新疫情得以蔓延。我们不禁要问,如果该行动的组织者花时间反思并重新调整战略,依靠扩大免疫规划的常规疫苗接种,而这种接种不会引发此类反对,情况会变成什么样。

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