Problems associated with epidural anesthesia in obstetrics.

Toxic reactions to bupivacaine and 2-chloroprocaine recently have been reported in parturients receiving epidural analgesia. Neurotoxicity has occurred after the accidental subarachnoid injection of large doses of 2-chloroprocaine. Cardiac arrest and death have occurred after the accidental intravascular injection of bupivacaine. Obstetricians should be aware of these hazards and how to avoid them by the use of proper technique.