微流控和器官芯片用于疾病建模和药物筛选。
Microfluidics and Organ-on-a-Chip for Disease Modeling and Drug Screening.
机构信息
Science for Life Laboratory, Division of Nanobiotechnology, Department of Protein Science, KTH Royal Institute of Technology, 17165 Solna, Sweden.
Terasaki Institute for Biomedical Innovation, Los Angeles, CA 91367, USA.
出版信息
Biosensors (Basel). 2024 Feb 4;14(2):86. doi: 10.3390/bios14020086.
Abstract
The convergence of microfluidics and organ-on-a-chip (OoC) technologies has revolutionized our ability to create advanced models that recapitulate complex physiological processes [...].
摘要
微流控技术和器官芯片 (OoC) 技术的融合极大地提高了我们创建先进模型的能力，这些模型可以再现复杂的生理过程[... ]。
相似文献
1
Microfluidics and Organ-on-a-Chip for Disease Modeling and Drug Screening.微流控和器官芯片用于疾病建模和药物筛选。
Biosensors (Basel). 2024 Feb 4;14(2):86. doi: 10.3390/bios14020086.
2
Cardiovascular human organ-on-a-chip platform for disease modeling, drug development, and personalized therapy.用于疾病建模、药物开发和个性化治疗的心血管人体芯片器官平台。
J Biomed Mater Res A. 2024 Apr;112(4):512-523. doi: 10.1002/jbm.a.37602. Epub 2023 Sep 5.
3
Biosensors integrated 3D organoid/organ-on-a-chip system: A real-time biomechanical, biophysical, and biochemical monitoring and characterization.生物传感器集成的 3D 类器官/器官芯片系统：实时生物力学、生物物理和生物化学监测和表征。
Biosens Bioelectron. 2023 Jul 1;231:115285. doi: 10.1016/j.bios.2023.115285. Epub 2023 Apr 7.
4
Integrating Biosensors in Organs-on-Chip Devices: A Perspective on Current Strategies to Monitor Microphysiological Systems.将生物传感器集成到器官芯片设备中：监测微生理系统的当前策略视角。
Biosensors (Basel). 2020 Aug 28;10(9):110. doi: 10.3390/bios10090110.
5
Engineering Organ-on-a-Chip Systems for Vascular Diseases.用于血管疾病的器官芯片系统工程
Arterioscler Thromb Vasc Biol. 2023 Dec;43(12):2241-2255. doi: 10.1161/ATVBAHA.123.318233. Epub 2023 Oct 12.
6
From organ-on-chip to body-on-chip: The next generation of microfluidics platforms for in vitro drug efficacy and toxicity testing.从器官芯片到人体芯片：用于体外药物功效和毒性测试的下一代微流控平台。
Prog Mol Biol Transl Sci. 2022;187(1):41-91. doi: 10.1016/bs.pmbts.2021.07.019. Epub 2021 Aug 6.
7
Fitting tissue chips and microphysiological systems into the grand scheme of medicine, biology, pharmacology, and toxicology.将组织芯片和微生理系统融入医学、生物学、药理学和毒理学的整体框架之中。
Exp Biol Med (Maywood). 2017 Oct;242(16):1559-1572. doi: 10.1177/1535370217732765.
8
Revolutionizing Drug Discovery: The Impact of Distinct Designs and Biosensor Integration in Microfluidics-Based Organ-on-a-Chip Technology.颠覆药物发现：基于微流控的器官芯片技术中独特设计和生物传感器集成的影响。
Biosensors (Basel). 2024 Sep 3;14(9):425. doi: 10.3390/bios14090425.
9
A Comprehensive Review of Organ-on-a-Chip Technology and Its Applications.器官芯片技术及其应用的全面综述
Biosensors (Basel). 2024 May 1;14(5):225. doi: 10.3390/bios14050225.
10
Critical design parameters to develop biomimetic organ-on-a-chip models for the evaluation of the safety and efficacy of nanoparticles.开发用于评估纳米颗粒安全性和有效性的仿生芯片器官模型的关键设计参数。
Expert Opin Drug Deliv. 2023 Jan;20(1):13-30. doi: 10.1080/17425247.2023.2152000. Epub 2022 Dec 5.
引用本文的文献
1
A Lung Tumor-on-a-Chip Model Recapitulates the Effect of Hypoxia on Radiotherapy Response and FDG-PET Imaging.一种芯片上的肺肿瘤模型再现了缺氧对放疗反应和氟代脱氧葡萄糖正电子发射断层显像（FDG-PET）成像的影响。
bioRxiv. 2025 Jul 27:2025.07.23.666453. doi: 10.1101/2025.07.23.666453.
2
A lung tumor-on-a-chip model recapitulates the effect of hypoxia on radiotherapy response and FDG-PET imaging.一种芯片上的肺肿瘤模型概括了缺氧对放射治疗反应和氟代脱氧葡萄糖正电子发射断层显像（FDG-PET）成像的影响。
Lab Chip. 2025 Aug 5. doi: 10.1039/d5lc00373c.
3
Organ-on-a-chip systems for modeling tumor and normal tissue microenvironments in radiotherapy research.用于放射治疗研究中肿瘤和正常组织微环境建模的芯片器官系统。
Trends Biotechnol. 2025 Jul 24. doi: 10.1016/j.tibtech.2025.07.002.
4
Biomedical applications of organoids derived from the digestive system.源自消化系统的类器官的生物医学应用。
Front Cell Dev Biol. 2025 May 30;13:1599384. doi: 10.3389/fcell.2025.1599384. eCollection 2025.
5
The utilisation of biliary organoids for biomedical applications.胆管类器官在生物医学应用中的利用。
Front Bioeng Biotechnol. 2025 Jan 7;12:1501829. doi: 10.3389/fbioe.2024.1501829. eCollection 2024.
6
Advances in Microfluidic Cochlea-On-A-Chip.微流控耳蜗芯片的进展
Adv Sci (Weinh). 2025 Aug;12(29):e2406077. doi: 10.1002/advs.202406077. Epub 2024 Dec 23.
7
Microfluidic Gastrointestinal Cell Culture Technologies-Improvements in the Past Decade.微流控胃肠道细胞培养技术-过去十年的改进。
Biosensors (Basel). 2024 Sep 19;14(9):449. doi: 10.3390/bios14090449.
Zotero 插件