Hakulinen T, Abeywickrama K H
Comput Programs Biomed. 1985;19(2-3):197-207. doi: 10.1016/0010-468x(85)90011-x.
A computer program package has been constructed for use in patient survival analyses for chronic diseases based on aggregated data. The central concept of the analyses--the relative survival rate--is the ratio of the observed survival rate of the patients to the survival rate expected in a group in the general population similar to the group of patients at the beginning of the follow-up (interval), with respect to age, sex and calendar time. This quantity is used to measure patient survival adjusted for the effect of mortality attributable to the competing risks of death without employing information on causes of death of individual patients. The package contains three alternative methods of estimating the relative survival rates, two different ways of estimating the expectation of life for the patients, and five methods of testing the relative survival patterns using information on the whole follow-up period. Conventional survival and competing risk analysis can also be performed with the package. It is hoped that the package will facilitate standardization of statistical methodology and terminology in long-term survival studies for chronic diseases.
已构建了一个计算机程序包,用于基于汇总数据对慢性病患者进行生存分析。分析的核心概念——相对生存率——是患者观察到的生存率与在随访(时间段)开始时与患者组类似的一般人群中一组预期生存率的比值,该比值是根据年龄、性别和日历时间计算得出的。这个量用于衡量在不使用个体患者死亡原因信息的情况下,针对因死亡的竞争风险导致的死亡率影响进行调整后的患者生存率。该程序包包含三种估计相对生存率的替代方法、两种估计患者预期寿命的不同方式,以及五种使用整个随访期信息检验相对生存模式的方法。使用该程序包还可以进行传统的生存分析和竞争风险分析。希望该程序包将有助于慢性病长期生存研究中统计方法和术语的标准化。