Teaching and Experimental Center, Guangdong Pharmaceutical University, Guangzhou 510006, China.
School of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Molecules. 2024 Feb 8;29(4):788. doi: 10.3390/molecules29040788.
, which is found widely distributed across the Asian region, functions as both an economic tree and a medicinal plant with a rich historical background. Previous investigations into its chemical composition and biological activity have predominantly centered on volatile components, leaving the study of non-volatile components relatively unexplored. In this study, we employed UPLC-HRMS technology to analyze the non-volatile components of branches and leaves, which successfully resulted in identifying 72 constituents. Comparative analysis between branches and leaves unveiled alkaloids, organic acids, and flavonoids as the major components. However, noteworthy differences in the distribution of these components between branches and leaves were observed, with only eight shared constituents, indicating substantial chemical variations in different parts of . Particularly, 24 compounds were identified for the first time from this plant. The assessment of antioxidant activity using four methods (ABTS, DPPH, FRAP, and CUPRAC) demonstrated remarkable antioxidant capabilities in both branches and leaves, with slightly higher efficacy observed in branches. This suggests that may act as a potential natural antioxidant with applications in health and therapeutic interventions. In conclusion, the chemical composition and antioxidant activity of provides a scientific foundation for its development and utilization in medicine and health products, offering promising avenues for the rational exploitation of resources in the future.
，广泛分布于亚洲地区，既是一种经济树种，也是一种具有丰富历史背景的药用植物。先前对其化学成分和生物活性的研究主要集中在挥发性成分上，而对非挥发性成分的研究相对较少。在这项研究中，我们采用 UPLC-HRMS 技术分析了树枝和树叶的非挥发性成分，成功鉴定出 72 种成分。树枝和树叶之间的比较分析表明，生物碱、有机酸和类黄酮是主要成分。然而，在树枝和树叶之间观察到这些成分的分布存在显著差异，只有 8 种共有成分，表明 在不同部位存在大量的化学变化。特别是，从这种植物中首次鉴定出 24 种化合物。采用四种方法（ABTS、DPPH、FRAP 和 CUPRAC）评估抗氧化活性，结果表明树枝和树叶均具有显著的抗氧化能力，树枝的效果略高。这表明 可能是一种潜在的天然抗氧化剂，可应用于健康和治疗干预。总之，的化学成分和抗氧化活性为其在医药和保健品中的开发和利用提供了科学基础，为未来合理开发 资源提供了有前景的途径。
