• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

猪流行性腹泻病毒和严重急性呼吸综合征冠状病毒 2 研究现状的比较综述:冠状病毒知识范围

Comparative Review of the State of the Art in Research on the Porcine Epidemic Diarrhea Virus and SARS-CoV-2, Scope of Knowledge between Coronaviruses.

机构信息

Centro de Química, Laboratorio de Bioquímica y Biología Molecular, Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla, Puebla 72570, Mexico.

Posgrado en Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla 72570, Mexico.

出版信息

Viruses. 2024 Feb 2;16(2):238. doi: 10.3390/v16020238.

DOI:10.3390/v16020238
PMID:38400014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10892376/
Abstract

This review presents comparative information corresponding to the progress in knowledge of some aspects of infection by the porcine epidemic diarrhea virus (PEDV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronaviruses. PEDV is an alphacoronavirus of great economic importance due to the million-dollar losses it generates in the pig industry. PEDV has many similarities to the SARS-CoV-2 betacoronavirus that causes COVID-19 disease. This review presents possible scenarios for SARS-CoV-2 based on the collected literature on PEDV and the tools or strategies currently developed for SARS-CoV-2 that would be useful in PEDV research. The speed of the study of SARS-CoV-2 and the generation of strategies to control the pandemic was possible due to the knowledge derived from infections caused by other human coronaviruses such as severe acute respiratory syndrome (SARS) and middle east respiratory syndrome (MERS). Therefore, from the information obtained from several coronaviruses, the current and future behavior of SARS-CoV-2 could be inferred and, with the large amount of information on the virus that causes COVID-19, the study of PEDV could be improved and probably that of new emerging and re-emerging coronaviruses.

摘要

这篇综述介绍了猪流行性腹泻病毒(PEDV)和严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)冠状病毒某些感染方面知识进展的对比信息。PEDV 是一种具有重要经济意义的α冠状病毒,因为它给养猪业造成了数百万美元的损失。PEDV 与导致 COVID-19 疾病的 SARS-CoV-2β冠状病毒有许多相似之处。本综述根据 PEDV 的文献综述和目前针对 SARS-CoV-2 开发的工具或策略,提出了基于 SARS-CoV-2 的可能情况,这些策略对 PEDV 的研究将非常有用。由于从其他人类冠状病毒(如严重急性呼吸综合征(SARS)和中东呼吸综合征(MERS))引起的感染中获得了知识,因此 SARS-CoV-2 的研究速度和控制大流行的策略的制定成为可能。因此,可以从几种冠状病毒获得的信息中推断出 SARS-CoV-2 的当前和未来行为,并且由于有大量关于导致 COVID-19 的病毒的信息,因此可以改进对 PEDV 的研究,并且可能对新出现和重新出现的冠状病毒进行研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d6/10892376/b68cbac2ff06/viruses-16-00238-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d6/10892376/b68cbac2ff06/viruses-16-00238-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d6/10892376/b68cbac2ff06/viruses-16-00238-g001.jpg

相似文献

1
Comparative Review of the State of the Art in Research on the Porcine Epidemic Diarrhea Virus and SARS-CoV-2, Scope of Knowledge between Coronaviruses.猪流行性腹泻病毒和严重急性呼吸综合征冠状病毒 2 研究现状的比较综述:冠状病毒知识范围
Viruses. 2024 Feb 2;16(2):238. doi: 10.3390/v16020238.
2
Structural Basis for the Inhibition of Host Gene Expression by Porcine Epidemic Diarrhea Virus nsp1.猪流行性腹泻病毒nsp1抑制宿主基因表达的结构基础
J Virol. 2018 Feb 12;92(5). doi: 10.1128/JVI.01896-17. Print 2018 Mar 1.
3
Porcine Epidemic Diarrhea Virus Deficient in RNA Cap Guanine-N-7 Methylation Is Attenuated and Induces Higher Type I and III Interferon Responses.猪流行性腹泻病毒 RNA 帽结构鸟嘌呤-N-7 甲基化缺陷型减毒活疫苗及其诱导的Ⅰ型和Ⅲ型干扰素应答。
J Virol. 2020 Jul 30;94(16). doi: 10.1128/JVI.00447-20.
4
Swine coronaviruses (SCoVs) and their emerging threats to swine population, inter-species transmission, exploring the susceptibility of pigs for SARS-CoV-2 and zoonotic concerns.猪冠状病毒 (SCoVs) 及其对猪群的新兴威胁、种间传播、探索猪对 SARS-CoV-2 的易感性和人畜共患问题。
Vet Q. 2022 Dec;42(1):125-147. doi: 10.1080/01652176.2022.2079756.
5
Coronaviruses Nsp5 Antagonizes Porcine Gasdermin D-Mediated Pyroptosis by Cleaving Pore-Forming p30 Fragment.冠状病毒 Nsp5 通过切割形成孔的 p30 片段拮抗猪源性 Gasdermin D 介导热激细胞死亡。
mBio. 2022 Feb 22;13(1):e0273921. doi: 10.1128/mbio.02739-21. Epub 2022 Jan 11.
6
Coronavirus Endoribonuclease Activity in Porcine Epidemic Diarrhea Virus Suppresses Type I and Type III Interferon Responses.冠状病毒内切核酸酶活性在猪流行性腹泻病毒中抑制 I 型和 III 型干扰素反应。
J Virol. 2019 Apr 3;93(8). doi: 10.1128/JVI.02000-18. Print 2019 Apr 15.
7
Melatonin and other indoles show antiviral activities against swine coronaviruses in vitro at pharmacological concentrations.褪黑素和其他吲哚类物质在药理学浓度下对猪冠状病毒表现出体外抗病毒活性。
J Pineal Res. 2021 Sep;71(2):e12754. doi: 10.1111/jpi.12754. Epub 2021 Jun 24.
8
Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model.全基因组减毒细菌表面表达的冠状病毒融合肽疫苗可预防猪模型中的疾病。
Proc Natl Acad Sci U S A. 2021 May 4;118(18). doi: 10.1073/pnas.2025622118.
9
Porcine Coronaviruses: Overview of the State of the Art.猪冠状病毒:研究现状概述。
Virol Sin. 2021 Oct;36(5):833-851. doi: 10.1007/s12250-021-00364-0. Epub 2021 Mar 15.
10
Porcine Epidemic Diarrhea Virus Inhibits HDAC1 Expression To Facilitate Its Replication via Binding of Its Nucleocapsid Protein to Host Transcription Factor Sp1.猪流行性腹泻病毒通过其核衣壳蛋白与宿主转录因子 Sp1 结合抑制 HDAC1 表达促进其复制。
J Virol. 2021 Aug 25;95(18):e0085321. doi: 10.1128/JVI.00853-21.

引用本文的文献

1
POLM inhibits porcine epidemic diarrhea virus replication by degrading multiple viral structural proteins.POLM通过降解多种病毒结构蛋白来抑制猪流行性腹泻病毒的复制。
J Virol. 2025 Mar 18;99(3):e0227824. doi: 10.1128/jvi.02278-24. Epub 2025 Feb 10.
2
Targeting pseudoknots with Cas13b inhibits porcine epidemic diarrhoea virus replication.利用Cas13b靶向假结可抑制猪流行性腹泻病毒的复制。
J Gen Virol. 2025 Feb;106(2). doi: 10.1099/jgv.0.002071.
3
Targeting host integrated stress response: lead discovery of flavonoid compounds active against coronaviruses PEDV and PDCoV.

本文引用的文献

1
Omicron new variant BA.2.86 (Pirola): Epidemiological, biological, and clinical characteristics - a global data-based analysis.奥密克戎新变体 BA.2.86(皮罗拉):基于全球数据的流行病学、生物学和临床特征分析。
Eur Rev Med Pharmacol Sci. 2023 Oct;27(19):9470-9476. doi: 10.26355/eurrev_202310_33975.
2
Paediatric acute epididymo-orchitis temporally related to SARS-CoV-2 infection: A case series and review of the literature.与新型冠状病毒感染存在时间关联的小儿急性附睾睾丸炎:病例系列及文献综述
J Pediatr Urol. 2024 Feb;20(1):91-94. doi: 10.1016/j.jpurol.2023.09.017. Epub 2023 Sep 27.
3
From Alpha to Omicron: How Different Variants of Concern of the SARS-Coronavirus-2 Impacted the World.
靶向宿主整合应激反应:抗冠状病毒PEDV和PDCoV的黄酮类化合物的先导发现
RSC Med Chem. 2024 Dec 23. doi: 10.1039/d4md00846d.
4
A Nanobody of PEDV S1 Protein: Screening and Expression in .PEDV S1 蛋白的纳米抗体:筛选与表达
Biomolecules. 2024 Sep 4;14(9):1116. doi: 10.3390/biom14091116.
从阿尔法到奥密克戎:严重急性呼吸综合征冠状病毒2的不同关注变异株如何影响世界
Biology (Basel). 2023 Sep 21;12(9):1267. doi: 10.3390/biology12091267.
4
Emerging SARS-CoV-2 variants: Why, how, and what's next?新型严重急性呼吸综合征冠状病毒2变体:成因、方式及后续情况?
Cell Insight. 2022 May 2;1(3):100029. doi: 10.1016/j.cellin.2022.100029. eCollection 2022 Jun.
5
Porcine epidemic diarrhea virus (PEDV) ORF3 protein inhibits cellular type I interferon signaling through down-regulating proteins expression in RLRs-mediated pathway.猪流行性腹泻病毒(PEDV)ORF3 蛋白通过下调 RLRs 介导途径中的蛋白表达来抑制细胞 I 型干扰素信号通路。
Res Vet Sci. 2023 Jun;159:146-159. doi: 10.1016/j.rvsc.2023.03.022. Epub 2023 Mar 30.
6
Porcine Epidemic Diarrhea Virus Antagonizes Host IFN-λ-Mediated Responses by Tilting Transcription Factor STAT1 toward Acetylation over Phosphorylation To Block Its Activation.猪流行性腹泻病毒通过使转录因子 STAT1 偏向乙酰化而非磷酸化来倾斜,从而拮抗宿主 IFN-λ 介导的反应,阻止其激活。
mBio. 2023 Jun 27;14(3):e0340822. doi: 10.1128/mbio.03408-22. Epub 2023 Apr 13.
7
Porcine Epidemic Diarrhea Virus nsp7 Inhibits MDA5 Dephosphorylation to Antagonize Type I Interferon Production.猪流行性腹泻病毒nsp7抑制MDA5去磷酸化以拮抗I型干扰素的产生。
Microbiol Spectr. 2023 Mar 28;11(2):e0501722. doi: 10.1128/spectrum.05017-22.
8
SARS-CoV-2 NSP8 suppresses type I and III IFN responses by modulating the RIG-I/MDA5, TRIF, and STING signaling pathways.SARS-CoV-2 NSP8 通过调节 RIG-I/MDA5、TRIF 和 STING 信号通路来抑制 I 型和 III 型 IFN 反应。
J Med Virol. 2023 Apr;95(4):e28680. doi: 10.1002/jmv.28680.
9
SARS-CoV-2 NSP7 inhibits type I and III IFN production by targeting the RIG-I/MDA5, TRIF, and STING signaling pathways.严重急性呼吸综合征冠状病毒2(SARS-CoV-2)非结构蛋白7(NSP7)通过靶向视黄酸诱导基因I(RIG-I)/黑色素瘤分化相关基因5(MDA5)、TIR结构域衔接蛋白诱导干扰素β(TRIF)和干扰素基因刺激蛋白(STING)信号通路来抑制I型和III型干扰素的产生。
J Med Virol. 2023 Mar;95(3):e28561. doi: 10.1002/jmv.28561.
10
Editorial: The XBB.1.5 ('Kraken') Subvariant of Omicron SARS-CoV-2 and its Rapid Global Spread.社论:奥密克戎 SARS-CoV-2 的 XBB.1.5(“Kraken”)亚变体及其快速全球传播。
Med Sci Monit. 2023 Feb 1;29:e939580. doi: 10.12659/MSM.939580.