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猪流行性腹泻病毒和严重急性呼吸综合征冠状病毒 2 研究现状的比较综述:冠状病毒知识范围

Comparative Review of the State of the Art in Research on the Porcine Epidemic Diarrhea Virus and SARS-CoV-2, Scope of Knowledge between Coronaviruses.

机构信息

Centro de Química, Laboratorio de Bioquímica y Biología Molecular, Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla, Puebla 72570, Mexico.

Posgrado en Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla 72570, Mexico.

出版信息

Viruses. 2024 Feb 2;16(2):238. doi: 10.3390/v16020238.

Abstract

This review presents comparative information corresponding to the progress in knowledge of some aspects of infection by the porcine epidemic diarrhea virus (PEDV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronaviruses. PEDV is an alphacoronavirus of great economic importance due to the million-dollar losses it generates in the pig industry. PEDV has many similarities to the SARS-CoV-2 betacoronavirus that causes COVID-19 disease. This review presents possible scenarios for SARS-CoV-2 based on the collected literature on PEDV and the tools or strategies currently developed for SARS-CoV-2 that would be useful in PEDV research. The speed of the study of SARS-CoV-2 and the generation of strategies to control the pandemic was possible due to the knowledge derived from infections caused by other human coronaviruses such as severe acute respiratory syndrome (SARS) and middle east respiratory syndrome (MERS). Therefore, from the information obtained from several coronaviruses, the current and future behavior of SARS-CoV-2 could be inferred and, with the large amount of information on the virus that causes COVID-19, the study of PEDV could be improved and probably that of new emerging and re-emerging coronaviruses.

摘要

这篇综述介绍了猪流行性腹泻病毒(PEDV)和严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)冠状病毒某些感染方面知识进展的对比信息。PEDV 是一种具有重要经济意义的α冠状病毒,因为它给养猪业造成了数百万美元的损失。PEDV 与导致 COVID-19 疾病的 SARS-CoV-2β冠状病毒有许多相似之处。本综述根据 PEDV 的文献综述和目前针对 SARS-CoV-2 开发的工具或策略,提出了基于 SARS-CoV-2 的可能情况,这些策略对 PEDV 的研究将非常有用。由于从其他人类冠状病毒(如严重急性呼吸综合征(SARS)和中东呼吸综合征(MERS))引起的感染中获得了知识,因此 SARS-CoV-2 的研究速度和控制大流行的策略的制定成为可能。因此,可以从几种冠状病毒获得的信息中推断出 SARS-CoV-2 的当前和未来行为,并且由于有大量关于导致 COVID-19 的病毒的信息,因此可以改进对 PEDV 的研究,并且可能对新出现和重新出现的冠状病毒进行研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d6/10892376/b68cbac2ff06/viruses-16-00238-g001.jpg

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