血凝素运输突变体。

Haemagglutinin transport mutants.

作者信息

Garten W, Kuroda K, Schuy W, Naruse H, Scholtissek C, Klenk H D

出版信息

Vaccine. 1985 Sep;3(3 Suppl):227-9. doi: 10.1016/0264-410x(85)90112-4.

Abstract

Two mutants (ts1 and ts651) with a temperature sensitive defect in the intracellular transport of the haemagglutinin from the rough endoplasmic reticulum to the plasma membrane have been analysed. Nucleotide sequencing of the haemagglutinin revealed with each mutant two point mutations that are located in the stem region of the molecule.

摘要

已对两个在血凝素从糙面内质网到质膜的细胞内运输中存在温度敏感缺陷的突变体（ts1和ts651）进行了分析。血凝素的核苷酸测序显示，每个突变体在分子的茎区有两个点突变。