Klimov A, Prösch S, Schäfer J, Bucher D
Research Institute for Viral Preparations, Academy of Medical Sciences of the U.S.S.R., Moscow.
Arch Virol. 1992;122(1-2):143-61. doi: 10.1007/BF01321124.
Antigenic analysis of the haemagglutinin and matrix protein with corresponding sets of monoclonal antibodies as well as sequence analysis of HA-, M-, and NS-genes were carried out to establish antigenic and genetic relationships between four fowl plague virus (FPV) strains of H7 subtype. The data obtained revealed close genetic relatedness between the oldest known influenza A virus, A/chicken/Brescia/1902 (H7N7), and two FPV strains, A/FPV/Dobson (H7N7) and A/FPV/Weybridge (H7N7). These three strains apparently differ in all genes investigated from the A/FPV/Rostock isolate.
利用相应的单克隆抗体集对血凝素和基质蛋白进行抗原分析，并对HA、M和NS基因进行序列分析，以确定4株H7亚型禽瘟病毒（FPV）毒株之间的抗原和遗传关系。所获得的数据显示，已知最古老的甲型流感病毒A/鸡/布雷西亚/1902（H7N7）与两株FPV毒株A/FPV/多布森（H7N7）和A/FPV/韦布里奇（H7N7）之间存在密切的遗传相关性。这三株毒株在所有研究基因上与A/FPV/罗斯托克分离株明显不同。
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