喂食“自助式饮食”的大鼠棕色脂肪组织中解偶联蛋白及其mRNA的增加。
Increase of uncoupling protein and its mRNA in brown adipose tissue of rats fed on 'cafeteria diet'.
作者信息
Falcou R, Bouillaud F, Mory G, Apfelbaum M, Ricquier D
出版信息
Biochem J. 1985 Oct 1;231(1):241-4. doi: 10.1042/bj2310241.
Abstract
The effect of 'cafeteria diet' on mitochondrial uncoupling protein in brown adipose tissue of rats was examined. 'Cafeteria diet' induced an increase of the 32 kDa uncoupling protein in electrophoresed proteins of brown-fat mitochondria. Use of a cDNA probe corresponding to uncoupling-protein mRNA indicated that this mRNA was increased in rats fed on the 'cafeteria diet'. Nevertheless, this effect was weak compared with that observed in rats adapted to cold.
摘要
研究了“自助餐式饮食”对大鼠棕色脂肪组织中线粒体解偶联蛋白的影响。“自助餐式饮食”导致棕色脂肪线粒体电泳蛋白中32 kDa解偶联蛋白增加。使用与解偶联蛋白mRNA对应的cDNA探针表明，在喂食“自助餐式饮食”的大鼠中，这种mRNA增加。然而，与适应寒冷的大鼠相比，这种效应较弱。
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